DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tsu and RBM8A

DIOPT Version :9

Sequence 1:	NP_610454.2	Gene:	tsu / 35924	FlyBaseID:	FBgn0033378	Length:	165	Species:	Drosophila melanogaster
Sequence 2:	NP_005096.1	Gene:	RBM8A / 9939	HGNCID:	9905	Length:	174	Species:	Homo sapiens

Alignment Length:	168	Identity:	106/168 - (63%)
Similarity:	129/168 - (76%)	Gaps:	6/168 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MADVLDIDNA--EEFEVDEDGDQGIVRLKEKAKHRKGRGFGSDSNTREAI-HSYERVRNEDDDEL 62
            ||||||:..|  |:|.:|||||:.|.:||||||.||||||||:..:|..: ..|:.|..:.|
Human     1 MADVLDLHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGFGSEEGSRARMREDYDSVEQDGD--- 62

  Fly    63 EPGPQRSVEGWILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHKQA 127
            ||||||||||||||||.:||||.|::|.:||.:||||||||||||||||:.|||.||||||:|:|
Human    63 EPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEA 127

  Fly   128 LAAKEALNGAEIMGQTIQVDWCFVKGPKRVKKSEKRRR 165
            .||.|.|||.::|||.|.||||||:||.:.|:...|||
Human   128 QAAMEGLNGQDLMGQPISVDWCFVRGPPKGKRRGGRRR 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tsu	NP_610454.2	PBP2_NikA_DppA_OppA_like	10..>80	CDD:413028	43/72 (60%)
tsu	NP_610454.2	RRM_RBM8	67..154	CDD:409762	63/86 (73%)
RBM8A	NP_005096.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..70		39/71 (55%)
		RRM_RBM8	67..151	CDD:409762	61/83 (73%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	151..174		7/15 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159763
Domainoid	1	1.000	108	1.000	Domainoid score	I6481
eggNOG	1	0.900	-	-		E1_KOG0130
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3744
Inparanoid	1	1.050	214	1.000	Inparanoid score	I3635
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52620
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004710
OrthoInspector	1	1.000	-	-		oto89675
orthoMCL	1	0.900	-	-		OOG6_102283
Panther	1	1.100	-	-	LDO	PTHR45894
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1829
SonicParanoid	1	1.000	-	-		X3311
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.830