Protein Alignment tsu and NIFK

DIOPT Version :10

• Sequence 1: NP_610454.2
• Gene: tsu / 35924
• FlyBaseID: FBgn0033378
• Length: 165
• Species: Drosophila melanogaster
• Sequence 2: NP_115766.3
• Gene: NIFK / 84365
• HGNCID: 17838
• Length: 293
• Species: Homo sapiens
• Alignment Length: 156
• Identity: 33/156 - (21%)
• Similarity: 64/156 - (41%)
• Gaps: 38/156 - (24%)

  Fly     4 VLDIDNAEEFEVDEDGDQGIVRLKEKAKHRKGRGFGSDSNTREAIHSYERVRNEDDDELEPGPQR 68
            :|.::..|:.|..::    :.:::::...||                       ..::|.||
Human    11 ILSLNPQEDVEFQKE----VAQVRKRITQRK-----------------------KQEQLTPG--- 45

  Fly    69 SVEGWILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAAKEA 133
                 :::|..:.....|.:|...|..:|.:....|:..:|||.|||||.||:|:...|....|.
Human    46 -----VVYVRHLPNLLDETQIFSYFSQFGTVTRFRLSRSKRTGNSKGYAFVEFESEDVAKIVAET 105

  Fly   134 LNGAEIMGQTIQVDWCFVKGPKRVKK 159
            :|. .:.|:.:..  |....|::|.|
Human   106 MNN-YLFGERLLE--CHFMPPEKVHK 128

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tsu	NP_610454.2	PBP2_NikA_DppA_OppA_like	10..>80	CDD:445520	8/69 (12%)
		RRM_RBM8	67..154	CDD:409762	22/86 (26%)
NIFK	NP_115766.3	half-pint	2..>151	CDD:130706	33/156 (21%)
		RRM_NIFK_like	46..119	CDD:409748	21/75 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..239
		Interaction with MKI67	226..269
		hNIFK_binding	227..266	CDD:463489
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	271..293