Protein Alignment Pgm2a and PCM1

DIOPT Version :9

• Sequence 1: NP_610453.1
• Gene: Pgm2a / 35923
• FlyBaseID: FBgn0033377
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_010856.1
• Gene: PCM1 / 856652
• SGDID: S000000784
• Length: 557
• Species: Saccharomyces cerevisiae
• Alignment Length: 670
• Identity: 120/670 - (17%)
• Similarity: 216/670 - (32%)
• Gaps: 229/670 - (34%)

  Fly    41 CQIMDAVRAKDWDTLRKRLCTRISFGTAGLRACMRAGFDSMNELVVIQTAQGLCEYIKEQYPDPA 105
            |::.|       ||.|.: ..:.|:||||.|...:       .|..:..:.|:...::.
Yeast     9 CKLYD-------DTCRTK-NVQFSYGTAGFRTLAK-------NLDTVMFSTGILAVLRS------ 52

  Fly   106 DWSGRGIVFGYDGRYNSHRFAELSAIVFLNNDFKVWLFKRYVATPMVPFAILRLQCLAGVMVTAS 170
                    ....|:|                                          .|||:|||
Yeast    53 --------LKLQGQY------------------------------------------VGVMITAS 67

  Fly   171 HNPKEDNGYKVYWTNGAQIIPPHDEGIQESILNNLEPKGSSWDDSAMCSNTMLE----DPYDIVV 231
            |||.:|||.|:...:|:.::...:....:  |.|.....:::::..:....::|    |....||
Yeast    68 HNPYQDNGVKIVEPDGSMLLATWEPYAMQ--LANAASFATNFEEFRVELAKLIEHEKIDLNTTVV 130

  Fly   232 P------------PY------------FDILKKQLPC---------TSLEANGRCSLSFTYTAMH 263
            |            ||            |......|.|         |.|....:........|..
Yeast   131 PHIVVGRDSRESSPYLLRCLTSSMASVFHAQVLDLGCVTTPQLHYITDLSNRRKLEGDTAPVATE 195

  Fly   264 GVGYAF----VKQAFARINLKPFISV----------------------------CEQQEPDPEFP 296
            ...|:|    ..:.||...|:..:||                            .||.|...:..
Yeast   196 QDYYSFFIGAFNELFATYQLEKRLSVPKLFIDTANGIGGPQLKKLLASEDWDVPAEQVEVINDRS 260

  Fly   297 TTP-MPNPEEG----KTSLDLSIKTAKANSSQIILANDPDADRLAVAEVREDGSYKLFSGNEVGA 356
            ..| :.|.|.|    ||:..|....:.::...:..:.|.||||:....|.....:.|..|:::..
Yeast   261 DVPELLNFECGADYVKTNQRLPKGLSPSSFDSLYCSFDGDADRVVFYYVDSGSKFHLLDGDKIST 325

  Fly   357 LLGWW------------SLELHKMREPDCDVSNCVMIASTVSSKILRAMAEREGFQFFETLTGFK 409
            |...:            ||::..::....:.|:...|.:|:...:..            |.||.|
Yeast   326 LFAKFLSKQLELAHLEHSLKIGVVQTAYANGSSTAYIKNTLHCPVSC------------TKTGVK 378

  Fly   410 WMGNKAIELQQAG--------KTVLFA--FEEAIGFMVGTTVLDKDGVSAAGHLATMACYLRCKL 464
            .:.::|......|        .|::|:  |...|...:..:.|:.|.::    |.|:.|:... :
Yeast   379 HLHHEAATQYDIGIYFEANGHGTIIFSEKFHRTIKSELSKSKLNGDTLA----LRTLKCFSEL-I 438

  Fly   465 CMTLQEKLRDIYETYGFHTTVSSYVICRCPPVIEQIFERLRTWDEGKADTYPTSILNGEYEIENV 529
            ..|:.:.:.|:.      ..:::..|.:..|:         .|||...| .|..::.......::
Yeast   439 NQTVGDAISDML------AVLATLAILKMSPM---------DWDEEYTD-LPNKLVKCIVPDRSI 487

  Fly   530 RDLTTGFDSSTGDKKATLPTSSSSQMITFTFKNGLVVT--------LRTSGTEPKMKYYAEMCGK 586
                  |.::..::|...|.....       |..|||.        :|.||||..::.||| |
Yeast   488 ------FQTTDQERKLLNPVGLQD-------KIDLVVAKYPMGRSFVRASGTEDAVRVYAE-C-- 536

  Fly   587 PDEKNWAKLTNTMNTMVEAI 606
               |:.:||....:.:||.:
Yeast   537 ---KDSSKLGQFCDEVVEHV 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgm2a	NP_610453.1	PTZ00150	23..623	CDD:240294	120/670 (18%)
		PGM2	62..604	CDD:100092	113/645 (18%)
PCM1	NP_010856.1	PGM3	24..553	CDD:100088	115/645 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1109
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900