Protein Alignment Pgm2a and Pgm2l1

DIOPT Version :10

• Sequence 1: NP_610453.1
• Gene: Pgm2a / 35923
• FlyBaseID: FBgn0033377
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_001102924.1
• Gene: Pgm2l1 / 685076
• RGDID: 1583226
• Length: 621
• Species: Rattus norvegicus
• Alignment Length: 608
• Identity: 305/608 - (50%)
• Similarity: 419/608 - (68%)
• Gaps: 16/608 - (2%)

  Fly    17 LSGDPELDGEIRKWIRWDKCASTACQIMDAVRAKDWDTLRKRLCTRISFGTAGLRACMRAGFDSM 81
            |:|||:||..|.:|:||||...|..||.:.:|......||.|||.|::|||||||:.|.|||..:
  Rat    19 LTGDPQLDTAIGQWLRWDKNPKTKEQIENLLRNGMNKELRDRLCCRMTFGTAGLRSAMGAGFCYI 83

  Fly    82 NELVVIQTAQGLCEYIKEQYPDPADWSGRGIVFGYDGR------YNSHRFAELSAIVFLNNDFKV 140
            |:|.|||:.||:.:|::..:   :|:..||.|.|||.|      .:|.|.|:|:|.|.|..|..|
  Rat    84 NDLTVIQSTQGMYKYLERCF---SDFKQRGFVVGYDTRGQVTSSCSSQRLAKLTAAVLLAKDVPV 145

  Fly   141 WLFKRYVATPMVPFAILRLQCLAGVMVTASHNPKEDNGYKVYWTNGAQIIPPHDEGIQESILNNL 205
            :||.|||.||.||:|:..|:.:||||:|||||.||||||||||..||||..|||:.|.:.|...:
  Rat   146 YLFSRYVPTPFVPYAVQELKAVAGVMITASHNRKEDNGYKVYWETGAQITSPHDKEILKCIEECV 210

  Fly   206 EPKGSSWDDSAMCSNTMLEDPYDIVVPPYFDILKKQLPCTSLEANGRCSLSFTYTAMHGVGYAFV 270
            ||...||:|:.:.::.:.:||...:...|.:.|||  .|...:.|.:.:|.|.:|:.||||:.:|
  Rat   211 EPWDDSWNDNLVDTSPLKKDPLQDICRRYMEDLKK--ICFYRDLNSKTTLKFVHTSFHGVGHDYV 273

  Fly   271 KQAFARINLKPFISVCEQQEPDPEFPTTPMPNPEEGKTSLDLSIKTAKANSSQIILANDPDADRL 335
            :.||.....||.|.|.||::|||:|.|...||||||::.|:||::.|:..:::|:||.|||||||
  Rat   274 QLAFQVFGFKPPIPVPEQKDPDPDFSTVKCPNPEEGESVLELSLRLAEKENARIVLATDPDADRL 338

  Fly   336 AVAEVREDGSYKLFSGNEVGALLGWWSLELHKMREPDCDVSNCVMIASTVSSKILRAMAEREGFQ 400
            ||||::|:|.:|:|:|||:.||.|||..:..|..:|:.||.|..|:|:|||||||:|:|.:|||.
  Rat   339 AVAELQENGHWKVFTGNELAALFGWWMFDCWKKSKPNADVKNVYMLATTVSSKILKAIALKEGFH 403

  Fly   401 FFETLTGFKWMGNKAIELQQAGKTVLFAFEEAIGFMVGTTVLDKDGVSAAGHLATMACYLRCKLC 465
            |.|||.||||:|::..:|...||.|||||||:|||:.||:||||||||||..:|.||.:|..:.
  Rat   404 FEETLPGFKWIGSRIKDLLGHGKEVLFAFEESIGFLCGTSVLDKDGVSAAVVVAEMAAFLDARK- 467

  Fly   466 MTLQEKLRDIYETYGFHTTVSSYVICRCPPVIEQIFERLRTWDEGKADTYPTSILNGEYEIENVR 530
            :||.|:|..:|||||:|.:.:||.:|..||.|:.||||:|.::..|  .||.  ..|.:.|.:||
  Rat   468 VTLMEQLMKVYETYGYHMSKTSYFLCYDPPTIKTIFERIRNFESPK--EYPK--FCGAFAILHVR 528

  Fly   531 DLTTGFDSSTGDKKATLPTSSSSQMITFTFKNGLVVTLRTSGTEPKMKYYAEMCGKPDEKNWAKL 595
            |:|||:|||..:||:.||.|.:||||||||:||.|.||||||||||:|||||||..|.:.:.|.|
  Rat   529 DITTGYDSSQPNKKSVLPVSKNSQMITFTFQNGCVATLRTSGTEPKIKYYAEMCASPGQSDTALL 593

  Fly   596 TNTMNTMVEAIVEEFYEPSKNGL 618
            ...:..:::|::|.|.|||||||
  Rat   594 EEELKKLIDALIENFLEPSKNGL 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgm2a	NP_610453.1	PTZ00150	23..623	CDD:240294	301/602 (50%)
Pgm2l1	NP_001102924.1	PTZ00150	24..620	CDD:240294	301/603 (50%)