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Protein Alignment Pgm2a and Pgm2

DIOPT Version :9

Sequence 1:	NP_610453.1	Gene:	Pgm2a / 35923	FlyBaseID:	FBgn0033377	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	NP_079976.1	Gene:	Pgm2 / 66681	MGIID:	97564	Length:	620	Species:	Mus musculus

Alignment Length:	614	Identity:	301/614 - (49%)
Similarity:	398/614 - (64%)	Gaps:	17/614 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LSGDPELDGEIRKWIRWDKCASTACQIMDAVRAKDWDTLRKRLCTRISFGTAGLRACMRAGFDSM 81
            |..|..||.|..:|:|||:...|:..:...:...:.:.|||....|:.||||||||.|.||...|
Mouse    17 LGMDARLDQETAQWLRWDQNPLTSESVKQLIAGGNKEELRKCFGARMEFGTAGLRAPMGAGISRM 81

  Fly    82 NELVVIQTAQGLCEYIKEQYPDPADWSGRGIVFGYDGRY------NSHRFAELSAIVFLNNDFKV 140
            |:|.:|||.||.|.|:::|:   :|...||:|..:|.|.      :|.|||.|:|..|:.....|
Mouse    82 NDLTIIQTTQGFCRYLEKQF---SDLKQRGVVISFDARAHPASGGSSRRFARLAATAFITQGVPV 143

  Fly   141 WLFKRYVATPMVPFAILRLQCLAGVMVTASHNPKEDNGYKVYWTNGAQIIPPHDEGIQESILNNL 205
            :||.....||.||:.:..|:..||:|:|||||||:||||||||.||||||.|||.||.::|..||
Mouse   144 YLFSDITPTPFVPYTVSHLKLCAGIMITASHNPKQDNGYKVYWDNGAQIISPHDRGISQAIEENL 208

  Fly   206 EPKGSSWDDSAMCSNTMLEDPYDIVVPPYFDILKKQLPCTSLEANGRCSLSFTYTAMHGVGYAFV 270
            ||...:|::|.:.|:.:|.:|...:...||:.|||.  |.....|....:.|.:|::||||:.||
Mouse   209 EPWPQAWEESLVDSSPLLHNPSASIGNDYFEDLKKY--CFHRTVNKESKVKFVHTSVHGVGHEFV 271

  Fly   271 KQAFARINLKPFISVCEQQEPDPEFPTTPMPNPEEGKTSLDLSIKTAKANSSQIILANDPDADRL 335
            :.||...:|.|..:|.:|::|||||||...|||||||..|.||...|....::|:||||||||||
Mouse   272 QLAFKAFDLAPPEAVPQQKDPDPEFPTVKYPNPEEGKGVLTLSFALADKIKAKIVLANDPDADRL 336

  Fly   336 AVAEVREDGSYKLFSGNEVGALLGWWSLELHKMREPD-CDVSNCVMIASTVSSKILRAMAEREGF 399
            ||||.::.|.:::|||||:|||||||.....|.:..| .::.:..|::||||||||||:|.:|||
Mouse   337 AVAEKQDSGEWRVFSGNELGALLGWWLFTSWKEKNQDQSNLKDTYMLSSTVSSKILRAIALKEGF 401

  Fly   400 QFFETLTGFKWMGNKAIELQQAGKTVLFAFEEAIGFMVGTTVLDKDGVSAAGHLATMACYLRCKL 464
            .|.|||||||||||:|.:|...|||||||||||||:|....||||||||||...|.:|.:|..|
Mouse   402 HFEETLTGFKWMGNRAQQLGDQGKTVLFAFEEAIGYMCCPFVLDKDGVSAAVICAELASFLATK- 465

  Fly   465 CMTLQEKLRDIYETYGFHTTVSSYVICRCPPVIEQIFERLRTWDEGKADTYPTSILNGEYEIENV 529
            .::|.::|..||..||:|.|.:||.||.....|:.:|..||.:| || :.||.  :.|::||..:
Mouse   466 NLSLSQQLNAIYVEYGYHITTASYFICHDQGTIQNLFGNLRNYD-GK-NNYPK--MCGKFEISAI 526

  Fly   530 RDLTTGFDSSTGDKKATLPTSSSSQMITFTFKNGLVVTLRTSGTEPKMKYYAEMCGKPDEKNWAK 594
            ||||||:|.|..||||.||||.|||||||||.||.|.|:||||||||:|||||:|..|...:...
Mouse   527 RDLTTGYDDSQPDKKAVLPTSKSSQMITFTFANGGVATMRTSGTEPKIKYYAELCAPPGNSDPEH 591

  Fly   595 LTNTMNTMVEAIVEEFYEPSKNGLQRRKE 623
            |...::.:|.||.|.|::|.|..||.:.|
Mouse   592 LKKELDELVGAIEEHFFQPQKYNLQPKAE 620

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.