Protein Alignment Pgm2a and pgm2l1

DIOPT Version :9

• Sequence 1: NP_610453.1
• Gene: Pgm2a / 35923
• FlyBaseID: FBgn0033377
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_001091955.1
• Gene: pgm2l1 / 449945
• ZFINID: ZDB-GENE-041008-205
• Length: 619
• Species: Danio rerio
• Alignment Length: 625
• Identity: 302/625 - (48%)
• Similarity: 407/625 - (65%)
• Gaps: 17/625 - (2%)

  Fly     4 SGGQMLCEIKNMALSGDPELDGEIRKWIRWDKCASTACQIMDAVRAKDWDTLRKRLCTRISFGTA 68
            |.|.:....:.::.:|||.||..:.:|:.|||...|..||...|:......||:|||:|::||||
Zfish     3 SNGDLNANSQCLSATGDPVLDKAVSQWMTWDKNPLTREQIESLVQEGRVVELRRRLCSRMTFGTA 67

  Fly    69 GLRACMRAGFDSMNELVVIQTAQGLCEYIKEQYPDPADWSGRGIVFGYDGR------YNSHRFAE 127
            ||||.|.|||..:|:|.:||:.|||.:|:.:.:|   |...||:|.|||.|      ..|.|.|:
Zfish    68 GLRAAMGAGFARINDLTIIQSTQGLYKYLAKCFP---DLKTRGLVVGYDTRAQASSGCTSERLAK 129

  Fly   128 LSAIVFLNNDFKVWLFKRYVATPMVPFAILRLQCLAGVMVTASHNPKEDNGYKVYWTNGAQIIPP 192
            |:|.|.|..|..|:||..||.||.||:|:::....||||:|||||.||||||||||.|||||..|
Zfish   130 LTAAVMLCKDVPVYLFSTYVPTPFVPYAVMKYGAAAGVMITASHNRKEDNGYKVYWHNGAQIASP 194

  Fly   193 HDEGIQESILNNLEPKGSSWDDSAMCSNTMLEDPYDIVVPPYFDILKKQLPCTSLEANGRCSLSF 257
            ||:.|...|..:.||...||::..:.::.:..||.:.|...|.:.|...  |...|.|.:..|.|
Zfish   195 HDKEILHCIEESAEPWAESWNEDLVENSLLKRDPLEDVCHWYMEELNTL--CFHRELNAKSPLKF 257

  Fly   258 TYTAMHGVGYAFVKQAFARINLKPFISVCEQQEPDPEFPTTPMPNPEEGKTSLDLSIKTAKANSS 322
            .:::.||||:.:|::||.:....|.|.|.||::|||:|.|...||||||::.|:||::.|:...:
Zfish   258 VHSSFHGVGHNYVQRAFQQFGFPPPIPVPEQKDPDPDFSTVSCPNPEEGESVLELSLRLAEREKA 322

  Fly   323 QIILANDPDADRLAVAEVREDGSYKLFSGNEVGALLGWWSLELHKMREPD-CDVSNCVMIASTVS 386
            :|::|.|||||||||||..::..:|:|:|||:.||||||.|...|...|| .|.....|:|:|||
Zfish   323 RIVVATDPDADRLAVAEQNDNCGWKVFTGNELAALLGWWMLFNWKEAHPDPADTERVYMLATTVS 387

  Fly   387 SKILRAMAEREGFQFFETLTGFKWMGNKAIELQQAGKTVLFAFEEAIGFMVGTTVLDKDGVSAAG 451
            ||||.|.|..|||.|.|||.||||:||:..||::|||.|:|:|||:|||:.|..||||||||.|.
Zfish   388 SKILEAFARIEGFHFEETLPGFKWIGNRIHELKKAGKEVIFSFEESIGFLCGNMVLDKDGVSTAA 452

  Fly   452 HLATMACYLRCKLCMTLQEKLRDIYETYGFHTTVSSYVICRCPPVIEQIFERLRTWDEGKADTYP 516
            .:|.||.||..| .::|.::|.:|||.||:|.:.:|||:|..||.|.:||.|||.:  |....||
Zfish   453 VVAEMASYLHTK-NLSLNQQLCNIYEIYGYHISRTSYVLCNDPPTIHRIFSRLRNF--GGQGVYP 514

  Fly   517 TSILNGEYEIENVRDLTTGFDSSTGDKKATLPTSSSSQMITFTFKNGLVVTLRTSGTEPKMKYYA 581
            ||.  |:|.|.::||:|||:|||..|||..||.|.||||:||||:||:|.||||||||||:|||.
Zfish   515 TSC--GDYCITHIRDVTTGYDSSQPDKKCVLPLSKSSQMLTFTFQNGIVATLRTSGTEPKIKYYT 577

  Fly   582 EMCGKPDEKNWAKLTNTMNTMVEAIVEEFYEPSKNGLQRR 621
            |.|..|.|::.:.|...:..:..|:||||.||.||.|..|
Zfish   578 EFCASPGERDISSLDEELRKVAAALVEEFLEPDKNDLLGR 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgm2a	NP_610453.1	PTZ00150	23..623	CDD:240294	297/606 (49%)
		PGM2	62..604	CDD:100092	271/548 (49%)
pgm2l1	NP_001091955.1	PTZ00150	22..618	CDD:240294	297/606 (49%)
		PGM2	61..600	CDD:100092	271/548 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	151	1.000	Domainoid score	I4314
eggNOG	1	0.900	-	-		E1_COG1109
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	576	1.000	Inparanoid score	I1006
OMA	1	1.010	-	-		QHG53730
OrthoDB	1	1.010	-	-		D1041556at2759
OrthoFinder	1	1.000	-	-		FOG0002126
OrthoInspector	1	1.000	-	-		mtm6464
orthoMCL	1	0.900	-	-		OOG6_100912
Panther	1	1.100	-	-	O	PTHR45745
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R913
SonicParanoid	1	1.000	-	-		X1578
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.870