Protein Alignment Pgm2a and Pgm3

DIOPT Version :9

• Sequence 1: NP_610453.1
• Gene: Pgm2a / 35923
• FlyBaseID: FBgn0033377
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_082628.3
• Gene: Pgm3 / 109785
• MGIID: 97566
• Length: 542
• Species: Mus musculus
• Alignment Length: 537
• Identity: 105/537 - (19%)
• Similarity: 175/537 - (32%)
• Gaps: 182/537 - (33%)

  Fly   155 AILR---LQCLAGVMVTASHNPKEDNGYKVYWTNGAQIIP------------------------- 191
            |:||   .:...||||||||||:||||.|:....|..:.|
Mouse    46 AVLRSKQTRSTIGVMVTASHNPEEDNGVKLVDPLGEMLAPSWEEHATCLASAEEQDVRQVLAAIV 110

  Fly   192 --------------------PHDEGIQESILNNLEPKGSSWDDSAMCSNTMLE------------ 224
                                |..|.:.:|:::.:...|..:.|..:.:...|.
Mouse   111 EKEAVDLTQTAFVVIARDTRPSSEKLSQSVIDGVTVLGGQFHDYGLLTTPQLHYMVYCRNSGGRY 175

  Fly   225 -----DPYDIVVPPYFDILKKQLPCTSLEANGRCSLSFTYTAMHGVGYAFVKQA---FAR-INLK 280
                 :.|...:...|..|..|:.|     :|....|......:|:|...:::.   |:| :::.
Mouse   176 GQATVEGYCQKLSKAFVDLTNQVSC-----SGDVKRSVKVDCANGIGALKLREMEHYFSRGLSVL 235

  Fly   281 PFIS--------------VCEQQEPDPEFPTTPMPNPEEGKTSLDLSIKTAKANSSQIILANDPD 331
            .|..              |..||:|         |...|.|             |.:...:.|.|
Mouse   236 LFNDGTQGRLNHLCGADFVKSQQKP---------PQGIEMK-------------SGERCCSFDGD 278

  Fly   332 ADRLAVAEVREDGSYKLFSGNEVGALLGWWSLELHKMREPDCDVSNCVMIASTVSSKILRAMAER 396
            |||:.......||.:.|..|:::..|:..:..||  :.|....|:..|:..:..:....|.:.|.
Mouse   279 ADRIVYYYCDADGHFHLIDGDKIATLISSFLKEL--LLEIGESVNLGVVQTAYANGSSTRYLEEV 341

  Fly   397 EGFQFFETLTGFKWMGNKAIELQ-----QAGKTVLFAFEEAIGFMVGTTV--LDKDGVSAAGHLA 454
            .....:.|.||.|.:.:||.|..     :|.......|.||:...:....  ||.....||..||
Mouse   342 MKVPVYCTKTGVKHLHHKAQEFDIGVYFEANGHGTALFSEAVEVKIKRLAQELDDGKGKAARTLA 406

  Fly   455 TMACYLRCKLCMTLQEKLRDIY-ETYGFHTTVSSYVICRCPPVIEQIFE----RLRTWDEGKADT 514
            ::.                |:: :..|  ..:|..:      |||.|..    .::.||....|
Mouse   407 SII----------------DLFNQAAG--DAISDML------VIEAILALKGLTVQQWDAIYVD- 446

  Fly   515 YPTSILNGEYEIENVRDLTTGFDSSTGDKKATLPTSSSSQMIT--------------FTFKNGLV 565
                :.|.:.:::            ..|::....|.:..|.:|              :|.....|
Mouse   447 ----LPNRQLKVK------------VADRRVISTTDAERQAVTPPGLQEAINDLVKKYTLARAFV 495

  Fly   566 VTLRTSGTEPKMKYYAE 582
               |.||||..::.|||
Mouse   496 ---RPSGTEDIVRVYAE 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgm2a	NP_610453.1	PTZ00150	23..623	CDD:240294	105/537 (20%)
		PGM2	62..604	CDD:100092	105/537 (20%)
Pgm3	NP_082628.3	PLN02895	1..538	CDD:215485	105/537 (20%)
		PGM3	22..527	CDD:100088	105/537 (20%)
		Substrate binding. /evidence=ECO:0000250|UniProtKB:Q9P4V2	370..372		0/1 (0%)
		Substrate binding. /evidence=ECO:0000250|UniProtKB:Q9P4V2	496..500		2/3 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1109
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900