DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8078 and Ctu1

DIOPT Version :9

Sequence 1:	NP_610451.1	Gene:	CG8078 / 35920	FlyBaseID:	FBgn0033375	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_001099721.1	Gene:	Ctu1 / 292847	RGDID:	1308740	Length:	382	Species:	Rattus norvegicus

Alignment Length:	317	Identity:	170/317 - (53%)
Similarity:	227/317 - (71%)	Gaps:	10/317 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RAALKRPKTGDALCKECFFAAFEAEIHHTISSSNLFRRGEKVAVAASGGKDSTVLAHVLKLLNER 76
            ||||:||::|.|||..||.||||||:..|:.:.:|..:|..|||.||||||||||||||:.|..|
  Rat    13 RAALRRPRSGQALCGPCFCAAFEAEVLRTVLAGHLLPQGAVVAVGASGGKDSTVLAHVLRELAPR 77

  Fly    77 HNYGLELVLLSIDEGITGYRDDSLETVKQNRDDYQMPLKILSYEELY-GWTMD---RIVAQIGRS 137
              .|:.|.|:::||||.||||.:||.|:.....:::||.|::||:|: |||||   |..|..|||
  Rat    78 --LGITLHLVAVDEGIGGYRDAALEAVRSQAARWELPLTIVAYEDLFGGWTMDAVARSTAGSGRS 140

  Fly   138 NN-CTFCGVFRRQALDRGAKLLGVDSIATGHNADDIAETVLMNVLRGDTARLRRCTSIRTGGGED 201
            .: ||||||.||:||:.||:|:|...|.|||||||:|||||||.||||..||.|...:.:.|...
  Rat   141 RSCCTFCGVLRRRALEEGARLVGATHIVTGHNADDMAETVLMNFLRGDAGRLARGGVLGSTGEGC 205

  Fly   202 TIPRVKPLKYSYEKEIVMYAHYKKLVYFSTECVFAPNAYRGHARAFLKDLEKVRPSVIMDIIYSG 266
            .:||.:||:::.:||:|:|||::.|.|||.|||:||.|:|||||..||.||..|||.::|:::|.
  Rat   206 ALPRCRPLQFASQKEVVLYAHFRHLRYFSEECVYAPEAFRGHARDLLKLLEAARPSAVLDLVHSA 270

  Fly   267 EQLRFKDTVKKPERGTCTRCGFVSSQQPCKACVLLEGLNRGLPKLGIGKKSKGERMI 323
            |:|......|.|..|||:|||.::|.:.|:||.||:|||||||:|.||   ||.|::
  Rat   271 ERLALAPAAKPPPPGTCSRCGALASNKLCQACALLDGLNRGLPRLAIG---KGRRVL 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8078	NP_610451.1	TilS	28..311	CDD:223115	154/287 (54%)
		Alpha_ANH_like_II	52..239	CDD:238951	105/191 (55%)
		TIGR00269	203..304	CDD:129370	50/100 (50%)
Ctu1	NP_001099721.1	TilS	29..329	CDD:223115	160/301 (53%)
		Alpha_ANH_like_II	54..243	CDD:238951	105/190 (55%)
		TIGR00269	207..308	CDD:129370	50/100 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	350..382
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352940
Domainoid	1	1.000	186	1.000	Domainoid score	I3281
eggNOG	1	0.900	-	-		E1_COG0037
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	331	1.000	Inparanoid score	I2361
OMA	1	1.010	-	-		QHG62166
OrthoDB	1	1.010	-	-		D455439at33208
OrthoFinder	1	1.000	-	-		FOG0003810
OrthoInspector	1	1.000	-	-		oto96729
orthoMCL	1	0.900	-	-		OOG6_100947
Panther	1	1.100	-	-	LDO	PTHR11807
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3171
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770