DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8078 and tut-1

DIOPT Version :9

Sequence 1:	NP_610451.1	Gene:	CG8078 / 35920	FlyBaseID:	FBgn0033375	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_499865.1	Gene:	tut-1 / 176826	WormBaseID:	WBGene00017928	Length:	373	Species:	Caenorhabditis elegans

Alignment Length:	324	Identity:	192/324 - (59%)
Similarity:	246/324 - (75%)	Gaps:	2/324 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SQCGNRAALKRPKTGDALCKECFFAAFEAEIHHTISSSNLFRRGEKVAVAASGGKDSTVLAHVLK 71
            |.|.|.|.:::.|.|..||..||...||.::|..|.::.||:|||:||:.|||||||||||:|:|
Worm    14 SGCSNPAKIRKAKDGAQLCGPCFSRNFEDDVHEAIVNNKLFKRGERVAIGASGGKDSTVLAYVMK 78

  Fly    72 LLNERHNYGLELVLLSIDEGITGYRDDSLETVKQNRDDYQMPLKILSYEELYGWTMDRIVAQIGR 136
            .||:||:|||:|.||||||||.|||||||..|::||.:|.:||.||||.:|||||||.|||:||:
Worm    79 TLNDRHDYGLDLQLLSIDEGIKGYRDDSLLAVEKNRVEYGLPLTILSYRDLYGWTMDDIVAKIGK 143

  Fly   137 SNNCTFCGVFRRQALDRGAKLLGVDSIATGHNADDIAETVLMNVLRGDTARLRRCTSIRTGGGED 201
            .||||||||||||||||||..:|...:.|||||||:|||:||||||||.|||.|||:|.| |.|.
Worm   144 KNNCTFCGVFRRQALDRGAFKIGATKLVTGHNADDMAETLLMNVLRGDIARLERCTNIVT-GEEG 207

  Fly   202 TIPRVKPLKYSYEKEIVMYAHYKKLVYFSTECVFAPNAYRGHARAFLKDLEKVRPSVIMDIIYSG 266
            .:||.|||||.:|::|||||...:|.||.|||::|||||||:||.:::|||||.|..|:|:|.||
Worm   208 DLPRAKPLKYCFERDIVMYARTNQLEYFYTECIYAPNAYRGYARKYVRDLEKVHPRAILDLIRSG 272

  Fly   267 EQLRFKDTVKKPERGTCTRCGFVSSQQPCKACVLLEGLNRGLPKLGIGKKSKGERMIAKQNQEL 330
            |::..|..|:.|....|.|||:::||:.||||:|:||||.|...||: :|||..:.:..:..||
Worm   273 EKVSVKKEVEMPTLKICERCGYMTSQKLCKACLLIEGLNTGNTDLGV-RKSKKSKKVTVEADEL 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8078	NP_610451.1	TilS	28..311	CDD:223115	177/282 (63%)
		Alpha_ANH_like_II	52..239	CDD:238951	128/186 (69%)
		TIGR00269	203..304	CDD:129370	55/100 (55%)
tut-1	NP_499865.1	TilS	35..311	CDD:223115	174/276 (63%)
		Alpha_ANH_like_II	59..245	CDD:238951	128/186 (69%)
		TIGR00269	209..310	CDD:129370	55/100 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166472
Domainoid	1	1.000	250	1.000	Domainoid score	I1153
eggNOG	1	0.900	-	-		E1_COG0037
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13513
Inparanoid	1	1.050	395	1.000	Inparanoid score	I1118
Isobase	1	0.950	-	0	Normalized mean entropy	S923
OMA	1	1.010	-	-		QHG62166
OrthoDB	1	1.010	-	-		D455439at33208
OrthoFinder	1	1.000	-	-		FOG0003810
OrthoInspector	1	1.000	-	-		oto18782
orthoMCL	1	0.900	-	-		OOG6_100947
Panther	1	1.100	-	-	LDO	PTHR11807
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R260
SonicParanoid	1	1.000	-	-		X3171
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790