DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8078 and Y71H2B.5

DIOPT Version :9

Sequence 1:	NP_610451.1	Gene:	CG8078 / 35920	FlyBaseID:	FBgn0033375	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_497589.3	Gene:	Y71H2B.5 / 175380	WormBaseID:	WBGene00022195	Length:	957	Species:	Caenorhabditis elegans

Alignment Length:	229	Identity:	63/229 - (27%)
Similarity:	98/229 - (42%)	Gaps:	27/229 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 ISSSNLFRRGEKVAVAASGGKDSTVLAHVLKLLNERHN----YGLELVLLSIDEGITGYRDDSL- 100
            |....:.|.|:||.|..||||||..|.|:|:...:|.|    ...||..:::|.|...|....|
Worm   710 IHQLKMIRDGDKVLVCLSGGKDSLSLLHILRHYQQRCNKARSTSFELGAITVDPGSAEYNPRPLI 774

  Fly   101 ETVKQNRDDYQMPLKILSYEELYGWTMDRIVA---QIGRSNNCTFCGVFRRQALDRGAKLLGVDS 162
            |..::...||       .|||     .|.|.|   ..|..:.|.||...:|..|...|:|.|.:.
Worm   775 EYCRRLNIDY-------FYEE-----QDIIGAARKTPGLRSICAFCSRMKRGRLAAAAQLHGWNV 827

  Fly   163 IATGHNADDIAETVLMNVLR-GDTARLRRCTSIRTGGGEDTIPRVKPLKYSYEKEIVMYAHYKKL 226
            :|.|.:.||:||:..:...: |:.:.::...:.:.|    .:..::||....||.:..:|..|||
Worm   828 LAMGQHLDDLAESFFIAAFQNGNLSTMKAQYTTKDG----ALRVIRPLVMVREKALRNFAEDKKL 888

  Fly   227 VYFSTEC--VFAPNAYRGHARAFLKDLEKVRPSV 258
            ...:..|  .|.....|...:..|...|.:.|.:
Worm   889 PVVAENCPACFNQATERHRVKQLLAQQELIFPDL 922

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8078	NP_610451.1	TilS	28..311	CDD:223115	63/229 (28%)
		Alpha_ANH_like_II	52..239	CDD:238951	56/197 (28%)
		TIGR00269	203..304	CDD:129370	14/58 (24%)
Y71H2B.5	NP_497589.3	CsdA	56..493	CDD:223594
		AAT_I	75..487	CDD:302748
		Alpha_ANH_like_II	721..901	CDD:238951	56/195 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0037
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810