DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dbp45A and RH36

DIOPT Version :9

Sequence 1:	NP_476927.1	Gene:	Dbp45A / 35917	FlyBaseID:	FBgn0010220	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_173078.1	Gene:	RH36 / 838197	AraportID:	AT1G16280	Length:	491	Species:	Arabidopsis thaliana

Alignment Length:	455	Identity:	184/455 - (40%)
Similarity:	284/455 - (62%)	Gaps:	35/455 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ANPFQILGLRPWLVKQLTKLGLKGATPIQQKCIPAILAGQDCIGAAKTGSGKTFAFALPILERLS 70
            |..|:.|||..|.|:...:||::..||:|..|:|.||||:|.:|.|:||||||.|||||||.||:
plant    57 ATNFEGLGLAEWAVETCKELGMRKPTPVQTHCVPKILAGRDVLGLAQTGSGKTAAFALPILHRLA 121

  Fly    71 EEPVSHFALVLTPTHELAYQISEQFLVAGQAMGVRVCVVSGGTDQMVESQKLMQRPHIVVAMPGR 135
            |:|...||||:|||.|||:|::|||...|..:.:|..|:.||.|.:.::..|:.|||||:..|||
plant   122 EDPYGVFALVVTPTRELAFQLAEQFKALGSCLNLRCSVIVGGMDMLTQTMSLVSRPHIVITTPGR 186

  Fly   136 LADHLTGCDTFS--FDNLKYLVVDEADRMLNGDFDESLSIIERCLPKTRQNLFFSATM----KDF 194
            :...|.......  |...|:||:|||||:|:..|.:.|..|.:||||:||.|.|||||    :..
plant   187 IKVLLENNPDVPPVFSRTKFLVLDEADRVLDVGFQDELRTIFQCLPKSRQTLLFSATMTSNLQAL 251

  Fly   195 IKESSIFPIASDCFEWSQDSDVATVETLDQRYLLCADYD-RDMVLIEALRKYREENENANVMIFT 258
            ::.||     :..:.:.....:.||:||.|:::. .|.| :::.|:..|.: .|:....:.|||.
plant   252 LEHSS-----NKAYFYEAYEGLKTVDTLTQQFIF-EDKDAKELYLVHILSQ-MEDKGIRSAMIFV 309

  Fly   259 NTKKYCQLLSMTLKNMEIDNVCLHGFMRQKERVAALSRFKSNQIRTLIATDVAARGLDIPSVELV 323
            :|.:.||.||:.|..:|::|:.:|....|..|::|||:|||.::..|:|||||:||||||:|:||
plant   310 STCRTCQRLSLMLDELEVENIAMHSLNSQSMRLSALSKFKSGKVPILLATDVASRGLDIPTVDLV 374

  Fly   324 MNHMLPRTPKEYIHRVGRTARAGRKGMSISIFRFPRDLELLAAIEEEINTKLTEHPIDQRMVERI 388
            :|:.:||.|::|:|||||||||||.|:::||.. ..|::|:..||||:..|:  .|.:::::...
plant   375 INYDIPRDPRDYVHRVGRTARAGRGGLAVSIIT-ETDVKLIHKIEEEVGKKM--EPYNKKVITDS 436

  Fly   389 F--MQVNVTRRESEMQLDNNDFDERAQNYRRKTWIMEGKDPDQMEALYRKKQKDK-LREIRRKRK 450
            .  .:|:..:|.:.|::.:|.|:::.:: |||              |.||...|| |.:.|.||:
plant   437 LEVTKVSKAKRVAMMKMLDNGFEDKVKD-RRK--------------LKRKTLADKGLLKKRGKRQ 486

Fly 451 450
plant 487 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dbp45A	NP_476927.1	SrmB	8..490	CDD:223587	183/453 (40%)
		DEADc	9..197	CDD:238167	92/193 (48%)
		Helicase_C	239..346	CDD:278689	50/106 (47%)
RH36	NP_173078.1	SrmB	30..487	CDD:223587	184/455 (40%)
RH36	NP_173078.1	DEADc_DDX49	60..263	CDD:350713	94/207 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	113	1.000	Domainoid score	I2041
eggNOG	1	0.900	-	-		E2759_KOG0340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41308
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53695
OrthoDB	1	1.010	-	-		D744428at2759
OrthoFinder	1	1.000	-	-		FOG0001029
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102828
Panther	1	1.100	-	-	LDO	PTHR24031
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3550
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.790