Protein Alignment Dbp45A and Ddx54

DIOPT Version :10

• Sequence 1: NP_476927.1
• Gene: Dbp45A / 35917
• FlyBaseID: FBgn0010220
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001178477.2
• Gene: Ddx54 / 360815
• RGDID: 1562539
• Length: 874
• Species: Rattus norvegicus
• Alignment Length: 589
• Identity: 167/589 - (28%)
• Similarity: 265/589 - (44%)
• Gaps: 99/589 - (16%)

  Fly     2 QRKEANPFQILGLRPWLVKQLTKLGLKGATPIQQKCIPAILAGQDCIGAAKTGSGKTFAFALPIL 66
            ::|::..||.:||...:.|.:.|.|.|..||||:|.||.||.|:|.:..|:||||||..|.||:.
  Rat    90 KKKKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMF 154

  Fly    67 ERLS--EEPVSHFALVLTPTHELAYQISEQFLVAGQAMGVRVCVVSGGTDQMVESQKLMQRPHIV 129
            |||.  .......||:|:||.|||.|..:.....|:..|::..::.||.....:...|.:.|.|:
  Rat   155 ERLKARSAQTGARALILSPTRELALQTMKFTKELGKFTGLKTALILGGDKMEDQFAALHENPDII 219

  Fly   130 VAMPGRLADHLTGCDTFSFDNLKYLVVDEADRMLNGDFDESLSIIERCLPKTRQNLFFSATMK-- 192
            :|.||||. |:.........:::|:|.|||||:....|.|.|..|...||...|.:.||||:.
  Rat   220 IATPGRLV-HVAVEMNLKLQSVEYVVFDEADRLFEMGFAEQLQEIIGRLPGGHQTVLFSATLPKL 283

  Fly   193 --DFIKESSIFPIASDCFEWSQDSDVATVETLDQRYLLCADYDRDMVLIEALRK-YREENENANV 254
              :|.:.....|:..     ..|.|....|.|...:.|..:..:..||:..|:. .|.:::|
  Rat   284 LVEFARAGLTEPVLI-----RLDVDSKLNEQLKTSFFLVREDTKTAVLLYLLQNVVRPQDQN--- 340

  Fly   255 MIFTNTKKYCQLLSMTLKNMEIDNVCLHGFMRQKERVAALSRFKSNQIRTLIATDVAARGLDIPS 319
            ::|..||.:.:.|:..|....:....::..:.|..|...|::|..|:..|||.||:||||||||.
  Rat   341 VVFVATKHHAEYLTELLTGQGVSCAHIYSALDQTARKINLAKFTHNKCSTLIVTDLAARGLDIPL 405

  Fly   320 VELVMNHMLPRTPKEYIHRVGRTARAGRKGMSISIFR-----FPRDLEL-------LAAIEEEIN 372
            ::.|:|:..|...|.::|||||.|||||.|.:.|:..     :..||.|       ||...||.:
  Rat   406 LDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEVPYLLDLHLFLGRSVTLARPHEEPS 470

  Fly   373 T-----------KLTEHPID-------------------QRMVERIFMQVNVTR---------RE 398
            :           ::.:..:|                   ||:......|...:|         |.
  Rat   471 SAGAVGRDGVLGRVPQSVVDDEDSSLQTALQASLELQGLQRVANNAQQQYLRSRPAPSPESIKRA 535

  Fly   399 SEMQLD--------NNDFDE----------RAQNYRRKTWIME----GKDPDQMEALYRKKQKDK 441
            .|:.|.        ::.|:|          ..:|||.:|.|.|    .|||.. :.:..|:|:|:
  Rat   536 KELDLAELGLHPLFSSCFEEGELQRLRLVDSIKNYRTRTTIFEINASSKDPSS-QMMRAKRQRDR 599

  Fly   442 -----LREIRRKRKLQHAEPAASEEGKALLQDERFKSVDSARFEKKGKGRSRATQEDTPTKPLKR 501
                 ..:.|::|:...|:|....|.....:::..::|:....|..|:.:.|    ..|.:..||
  Rat   600 KAITSFHQGRQERQDGPADPVPQRELPQKEEEDMVETVEGVFTEVVGQKQPR----PGPNQGAKR 660

  Fly   502 LNKE 505
            ..||
  Rat   661 RRKE 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp45A	NP_476927.1	SrmB	9..381	CDD:440279	130/401 (32%)
Ddx54	NP_001178477.2	None