DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dbp45A and me31B

DIOPT Version :9

Sequence 1:	NP_476927.1	Gene:	Dbp45A / 35917	FlyBaseID:	FBgn0010220	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_523533.2	Gene:	me31B / 34364	FlyBaseID:	FBgn0004419	Length:	459	Species:	Drosophila melanogaster

Alignment Length:	415	Identity:	123/415 - (29%)
Similarity:	212/415 - (51%)	Gaps:	30/415 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 NPFQILGLRPWLVKQLTKLGLKGATPIQQKCIPAILAGQDCIGAAKTGSGKTFAFALPILERLSE 71
            |.|:...|:..|:..:.:.|.:..:|||:..||..|:|:|.:..||.|:|||.|:.:|:||::
  Fly    58 NEFEEFCLKRELLMGIFEKGWERPSPIQEAAIPIALSGKDVLARAKNGTGKTGAYCIPVLEQI-- 120

  Fly    72 EPVSHF--ALVLTPTHELAYQISEQFLVAGQAMGVRVCVVSGGTDQMVESQKLMQRPHIVVAMPG 134
            :|...:  |||:.||.|||.|.|:..:...:.:.:||.|.:|||....:..::.|:..:::|.||
  Fly   121 DPTKDYIQALVMVPTRELALQTSQICIELAKHLDIRVMVTTGGTILKDDILRIYQKVQLIIATPG 185

  Fly   135 RLADHLTGCDTFSFDNLKYLVVDEADRMLNGDFDESLSIIERCLPKTRQNLFFSA----TMKDFI 195
            |:.| |.........:.:.||:||||::|:.||...|..:...|||..|.|.|||    |:|:|:
  Fly   186 RILD-LMDKKVADMSHCRILVLDEADKLLSLDFQGMLDHVILKLPKDPQILLFSATFPLTVKNFM 249

  Fly   196 KESSIFPIASDCFEWSQDSDVATVETLDQRYLLCADYDRDMVLIEALRKYREENENANVMIFTNT 260
            ::....|...:..|      ..|::.:.|.|....:..:    :..|.....:.:....:||.|:
  Fly   250 EKHLREPYEINLME------ELTLKGVTQYYAFVQERQK----VHCLNTLFSKLQINQSIIFCNS 304

  Fly   261 KKYCQLLSMTLKNMEIDNVC--LHGFMRQKERVAALSRFKSNQIRTLIATDVAARGLDIPSVELV 323
            .:..:||:.  |..|:...|  :|..|.|..|......|:....|.|:.:|:..||:|:.:|.:|
  Fly   305 TQRVELLAK--KITELGYCCYYIHAKMAQAHRNRVFHDFRQGLCRNLVCSDLFTRGIDVQAVNVV 367

  Fly   324 MNHMLPRTPKEYIHRVGRTARAGRKGMSISIFRFPRDLELLAAIEEEINTKLTEHP--IDQRM-V 385
            :|...||..:.|:||:||:.|.|..|::|::..: .|...|..||:|:.|::...|  ||..: |
  Fly   368 INFDFPRMAETYLHRIGRSGRFGHLGIAINLITY-EDRFDLHRIEKELGTEIKPIPKVIDPALYV 431

  Fly   386 ERIFMQVNVTRRESEMQLDNNDFDE 410
            ..:...|..|...|::   ||..:|
  Fly   432 ANVGASVGDTCNNSDL---NNSANE 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dbp45A	NP_476927.1	SrmB	8..490	CDD:223587	122/414 (29%)
		DEADc	9..197	CDD:238167	67/193 (35%)
		Helicase_C	239..346	CDD:278689	31/108 (29%)
me31B	NP_523533.2	PTZ00424	60..422	CDD:185609	112/377 (30%)
		DEADc	60..260	CDD:238167	68/202 (34%)
		HELICc	270..398	CDD:238034	36/133 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451578
Domainoid	1	1.000	91	1.000	Domainoid score	I403
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840