Protein Alignment Dbp45A and Prp5

DIOPT Version :10

• Sequence 1: NP_476927.1
• Gene: Dbp45A / 35917
• FlyBaseID: FBgn0010220
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_573020.2
• Gene: Prp5 / 32464
• FlyBaseID: FBgn0030631
• Length: 1224
• Species: Drosophila melanogaster
• Alignment Length: 565
• Identity: 154/565 - (27%)
• Similarity: 239/565 - (42%)
• Gaps: 167/565 - (29%)

  Fly     3 RKEANPFQILG------LRPWL--------VKQLTKLGLKGATPIQQKCIPAILAGQDCIGAAKT 53
            |.:....|:.|      ::.|.        ::.|.:||.:..||||.:.||||::|:|.||.|||
  Fly   492 RSDLEGIQVKGKGCPKPIKTWAQCGVSKKEMEVLRRLGFEKPTPIQCQAIPAIMSGRDLIGIAKT 556

  Fly    54 GSGKTFAFALPILERLSEEPVSH-----FALVLTPTHELAYQISEQFLVAGQAMGVRVCVVSGGT 113
            |||||.||.||:...:.::|...     .|:::.||.||..||.:......:::|:|...|.|||
  Fly   557 GSGKTLAFILPMFRHILDQPSMEDGDGAIAIIMAPTRELCMQIGKDIRKFSKSLGLRPVCVYGGT 621

  Fly   114 DQMVESQKLMQRPHIVVAMPGRLADHLTGCDTFSFDNLK---YLVVDEADRMLNGDFD-ESLSII 174
            ....:..:|.:...|:|..|||:.|.| ..::....||:   |:|:||||||.:..|: :.:.||
  Fly   622 GISEQIAELKRGAEIIVCTPGRMIDML-AANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRII 685

  Fly   175 ERCLPKTRQNLFFSATMKDFIKESSIFPIASDCFEWSQDSDVATVETLDQRYL------------ 227
            :...| .||.:.||||          ||              ..:|.|.:|.|
  Fly   686 DNVRP-DRQTVMFSAT----------FP--------------RQMEALARRILKKPIEVIVGGRS 725

  Fly   228 -LCADYDRDMV----------LIEALRKYREENENANVMIFTNTKKYCQLLSMTLKNMEIDNVCL 281
             :|.:.::.:|          |:|.|..|:|.   .::::|.:.::...:|...|.......:.|
  Fly   726 VVCKEVEQHVVILNDDAKFFKLLELLGIYQEA---GSIIVFVDKQENADILLRDLMKASYPCMSL 787

  Fly   282 HGFMRQKERVAALSRFKSNQIRTLIATDVAARGLDIPSVELVMNHMLPRTPKEYIHRVGRTARAG 346
            ||.:.|.:|.:.:..|||.::|.||||.|||||||:..:.||:|:.:|...::|:||.|||.|||
  Fly   788 HGGIDQFDRDSTIIDFKSGKVRLLIATSVAARGLDVKDLILVVNYDVPNHYEDYVHRCGRTGRAG 852

  Fly   347 RKGMSISIFRFPRDLELLAAIEEEINTKLTEHPIDQRMVERIFMQVNVTRRESEMQLDNNDFDER 411
            :||   |.:.|                                    :|..:|....|
  Fly   853 KKG---SAYTF------------------------------------ITPEQSRYAGD------- 871

  Fly   412 AQNYRRKTWIMEGKD------PDQMEALYRKKQKDKLREIRRKRKLQHAEPAASEEGKALLQDER 470
                     |:...|      |.:::||:.:           .:.||.|      |||.:.....
  Fly   872 ---------IIRAMDLSGTLIPAELQALWTE-----------YKALQEA------EGKTVHTGGG 910

  Fly   471 FKSVDSARFEKKGKGRSRATQEDTPTKPLKRLNKEKPVAQKGRAD 515
            |          .|||.....||....|..|:|.|    |..|.||
  Fly   911 F----------SGKGFKFDEQEFNAAKESKKLQK----AALGLAD 941

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp45A	NP_476927.1	SrmB	9..381	CDD:440279	125/417 (30%)
Prp5	NP_573020.2	Trypan_PARP	<291..383	CDD:368653
		DEAD-like_helicase_N	454..899	CDD:475120	135/501 (27%)
		KH-I_DDX46	1121..1223	CDD:411901