Protein Alignment Dbp45A and Ddx49

DIOPT Version :10

• Sequence 1: NP_476927.1
• Gene: Dbp45A / 35917
• FlyBaseID: FBgn0010220
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001108495.2
• Gene: Ddx49 / 290660
• RGDID: 1311124
• Length: 480
• Species: Rattus norvegicus
• Alignment Length: 499
• Identity: 233/499 - (46%)
• Similarity: 323/499 - (64%)
• Gaps: 34/499 - (6%)

  Fly     9 FQILGLRPWLVKQLTKLGLKGATPIQQKCIPAILAGQDCIGAAKTGSGKTFAFALPILERLSEEP 73
            |..|.|..|||:|..:||||..||:|..||||||.|:||:|.||||||||.||.||||::|||:|
  Rat     4 FAELRLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDP 68

  Fly    74 VSHFALVLTPTHELAYQISEQFLVAGQAMGVRVCVVSGGTDQMVESQKLMQRPHIVVAMPGRLAD 138
            ...|.||||||.||||||:|||.|.|:.:|::.|::.||.|.:.::.:|.::||:|:|.||||||
  Rat    69 YGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVTQALELSRKPHVVIATPGRLAD 133

  Fly   139 HLTGCDTFSFDNLKYLVVDEADRMLN---GDFDESLSIIERCLPKTRQNLFFSATMKDFIKESSI 200
            ||...:||:...:::||:|||||:|.   .||...|..|...:|..||.|.||||:.|.:||  :
  Rat   134 HLRSSNTFNMKKIRFLVLDEADRLLEQGCTDFTADLETILSAVPARRQTLLFSATLTDTLKE--L 196

  Fly   201 FPIASD-CFEWSQDSDVATVETLDQRYLLCADYDRDMVLIEALRKYREENENANVMIFTNTKKYC 264
            ..:|:: .|.|...:.|.|||.|||||||..:..:|..|:..::.::::.|:.:::|||||.|.|
  Rat   197 QGLATNQPFFWEAQATVRTVEQLDQRYLLVPEKVKDAYLVHLVQTFQDQLEDCSIIIFTNTCKTC 261

  Fly   265 QLLSMTLKNMEIDNVCLHGFMRQKERVAALSRFKSNQIRTLIATDVAARGLDIPSVELVMNHMLP 329
            |:|.|.|:......|.||..|:||||.|||:||||:..|.|||||||:||||||:|::|:||..|
  Rat   262 QILCMMLRKFNFPTVALHSMMKQKERFAALARFKSSTYRILIATDVASRGLDIPTVQVVINHNTP 326

  Fly   330 RTPKEYIHRVGRTARAGRKGMSISIFRFPRDLELLAAIEEEINTKLTEHPIDQRMVERIFMQVNV 394
            ..||.|||||||||||||:|.:|::.. ..|:.||.||||||..:|.|..:::..|.:|..||||
  Rat   327 GLPKIYIHRVGRTARAGRQGQAITLVT-QYDIHLLHAIEEEIKQQLAELAVEEAQVLQILTQVNV 390

  Fly   395 TRRESEMQLDNNDFDERAQNYRRKTWIMEGKDPDQMEALYRKKQKDKLREIRRKRKLQHAEPAAS 459
            .|||.|::|:.:.|||:.:..:||..|:|||||| :||    |:|.:|.:|::
  Rat   391 VRRECEIKLEASHFDEKKEINKRKQMILEGKDPD-LEA----KRKAELAKIKQ------------ 438

  Fly   460 EEGKALLQDERFKS--VDSARFEKKGK-GRSRATQEDTPTKPLK 500
                   |:.|||.  ..:.|.:|.|. ||........|.:|.:
  Rat   439 -------QNRRFKEKVEQTLRQQKAGSTGRRSRPPRPRPQEPAR 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp45A	NP_476927.1	SrmB	9..381	CDD:440279	193/375 (51%)
Ddx49	NP_001108495.2	SrmB	1..380	CDD:440279	193/378 (51%)
		Spc7	<359..>460	CDD:197874	46/124 (37%)