DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dbp45A and SPAC823.08c

DIOPT Version :9

Sequence 1:	NP_476927.1	Gene:	Dbp45A / 35917	FlyBaseID:	FBgn0010220	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_593835.1	Gene:	SPAC823.08c / 2543571	PomBaseID:	SPAC823.08c	Length:	465	Species:	Schizosaccharomyces pombe

Alignment Length:	448	Identity:	186/448 - (41%)
Similarity:	264/448 - (58%)	Gaps:	36/448 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 QRKEA-NPFQILGLRPWLVKQLTKLGLKGATPIQQKCIPAILAGQDCIGAAKTGSGKTFAFALPI 65
            |..|| ..|:.||:...|.:...|||.|..|||||:.||.:|..:|.||.|:||||||.|||||:
pombe    40 QNNEAPKTFKELGVIDELCEACEKLGFKTPTPIQQEAIPVVLNKRDVIGLAQTGSGKTAAFALPV 104

  Fly    66 LERLSEEPVSHFALVLTPTHELAYQISEQFLVAGQAMGVRVCVVSGGTDQMVESQKLMQRPHIVV 130
            ::.|...|...||:||.||.||||||||||...|.::|||..|:.||.|.:.::..|.::||::|
pombe   105 IQELWNNPSPFFAVVLAPTRELAYQISEQFEAIGGSIGVRSVVIVGGMDMVTQAVALSKKPHVLV 169

  Fly   131 AMPGRLADHLTGCDTFSFDNLKYLVVDEADRMLNGDFDESLSIIERCLPKTRQNLFFSATMK--- 192
            ..||||.|||.....||..|||||::|||||:|:.||...:..|.:.:|..|:.|.|||||.
pombe   170 CTPGRLMDHLENTKGFSLKNLKYLIMDEADRLLDMDFGPIIDKILKIIPHERRTLLFSATMTSKV 234

  Fly   193 DFIKESSIF-PIASDCFEWSQDSDVATVETLDQRYLLCADYDRDMVLIEALRKYREENENA--NV 254
            :.::.:|:. |:     ..:..|..:||:||.||||......:|..|:..:      ||.|  ::
pombe   235 EKLQRASLHQPV-----RVAVSSKFSTVDTLIQRYLFFPFKHKDTYLVYLV------NELAGNSI 288

  Fly   255 MIFTNTKKYCQLLSMTLKNMEIDNVCLHGFMRQKERVAALSRFKSNQIRTLIATDVAARGLDIPS 319
            :||..|....|.|::.|:.:....:.|||.:.|..|:.||::|||....||:||||||||||||.
pombe   289 IIFARTVNDTQRLAILLRTLGFSAIPLHGQLSQSNRLGALNKFKSGARSTLVATDVAARGLDIPL 353

  Fly   320 VELVMNHMLPRTPKEYIHRVGRTARAGRKGMSISIFRFPRDLELLAAIEEEINTKLTEHPIDQRM 384
            |::|:|:.:|...|.|||||||||||||.|.||::.. ..|||....||..|..|:.|:.||:..
pombe   354 VDVVINYDIPTDSKAYIHRVGRTARAGRAGKSIALVT-QYDLEPFLRIEATIGKKMQEYEIDKEG 417

  Fly   385 VERIFMQVNVTRRESEMQLDNNDFDERAQNYRRKTWIMEGKDPDQMEALYRKKQKDKL 442
            |..:..:|...:||:.:|:       :..:.|||:   :||       |:.|:::|.|
pombe   418 VFLLSERVGEAQREAIIQM-------KEIHDRRKS---KGK-------LHTKRKRDDL 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dbp45A	NP_476927.1	SrmB	8..490	CDD:223587	183/441 (41%)
		DEADc	9..197	CDD:238167	92/190 (48%)
		Helicase_C	239..346	CDD:278689	48/108 (44%)
SPAC823.08c	NP_593835.1	PRK11192	46..455	CDD:236877	181/437 (41%)
		DEADc	48..249	CDD:238167	94/205 (46%)
		HELICc	261..386	CDD:238034	58/130 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53695
OrthoFinder	1	1.000	-	-		FOG0001029
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920