Protein Alignment Dbp45A and H20J04.4

DIOPT Version :9

• Sequence 1: NP_476927.1
• Gene: Dbp45A / 35917
• FlyBaseID: FBgn0010220
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001040789.1
• Gene: H20J04.4 / 186756
• WormBaseID: WBGene00019219
• Length: 561
• Species: Caenorhabditis elegans
• Alignment Length: 481
• Identity: 192/481 - (39%)
• Similarity: 297/481 - (61%)
• Gaps: 20/481 - (4%)

  Fly     9 FQILGLRPWLVKQLTKLGLKGATPIQQKCIPAILAGQDCIGAAKTGSGKTFAFALPILERLSEEP 73
            |..||:..|:.:||..:.:|.|||:|..|||.||.|.|.:|.|:||:|||.|||:|||::||.:|
 Worm    91 FSQLGVCSWITQQLQTMQIKTATPVQAACIPKILEGSDILGCARTGTGKTLAFAIPILQKLSVDP 155

  Fly    74 VSHFALVLTPTHELAYQISEQFLVAGQAMGVRVCVVSGGTDQMVESQKLMQRPHIVVAMPGRLAD 138
            ...:||:||||.|||:||:|||...|:.:.::..|:.||...:.::::|.:|||:|||.||||||
 Worm   156 YGIYALILTPTRELAFQIAEQFTALGKPITLKCSVIVGGRSLIHQARELSERPHVVVATPGRLAD 220

  Fly   139 HL-TGCDTFS--FDNLKYLVVDEADRMLNGDFDESLSIIERCLPKTRQNLFFSATMKDFI----K 196
            .: :..||.:  |..:::.|:|||||||.|.:::.|..|...:.:.||.|..|||:.:.|    :
 Worm   221 LIESDPDTIAKVFKKIQFFVLDEADRMLEGQYNDQLKPIFESISEKRQTLLLSATITNNINMLHR 285

  Fly   197 ESSIFPIASDCFEWSQDSDVATVETLDQRYLLCADYDRDMVLIEALRKYREENENANVMIFTNTK 261
            .|:..|.   .||.....|.:||:.|:|:|::|....:|..|:..::.|.|:|..::||||..|.
 Worm   286 VSTRKPY---FFEDKGKDDESTVDRLEQKYVVCPVAVKDAYLVYVVKNYSEKNPKSSVMIFAQTC 347

  Fly   262 KYCQLLSMTLKNMEIDNVCLHGFMRQKERVAALSRFKSNQIRTLIATDVAARGLDIPSVELVMNH 326
            :.||.|:...:.:......||..:.||:|:||||.|:|..::.:|.||||:||||||.|:||:||
 Worm   348 RECQALAYMFEGLGFRVGSLHSQIPQKQRLAALSAFRSKTLQVIICTDVASRGLDIPHVDLVVNH 412

  Fly   327 MLPRTPKEYIHRVGRTARAGRKGMSISIFRFPRDLELLAAIEEEINTKLTEHPIDQRMVERIFMQ 391
            .:|:.||.|||||||:|||||.|.::| |....|:|||.|:|:.|..||.|..:..:.|.:...|
 Worm   413 NVPQCPKTYIHRVGRSARAGRFGSALS-FVTQYDVELLQAVEQVIGKKLDELKVSPKHVTKYVTQ 476

  Fly   392 VNVTRRESEMQLDNNDFDERAQNYRRKTWIMEGKDPDQMEALYRKKQKDKLREIRRKRKLQHAEP 456
            |.|.::|:|::|:|..|.|:.:..|||..:|.|.|.|         :.|:..|..|.|::.:::.
 Worm   477 VLVAKKEAELKLENQKFGEKKEINRRKELLMSGMDED---------EADRHLEEMRTRRMTNSKR 532

  Fly   457 AASEEGKALLQDERFKSVDSARFEKK 482
            ...:....|.:.:||:...:|:..||
 Worm   533 KLEKISGQLDKRDRFQKKLAAKKVKK 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp45A	NP_476927.1	SrmB	8..490	CDD:223587	192/481 (40%)
		DEADc	9..197	CDD:238167	86/194 (44%)
		Helicase_C	239..346	CDD:278689	50/106 (47%)
H20J04.4	NP_001040789.1	SrmB	69..546	CDD:223587	187/467 (40%)
		DEADc	91..295	CDD:238167	88/206 (43%)
		Helicase_C	333..432	CDD:278689	49/98 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167246
Domainoid	1	1.000	108	1.000	Domainoid score	I4034
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41308
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S721
OMA	1	1.010	-	-		QHG53695
OrthoDB	1	1.010	-	-		D314577at33208
OrthoFinder	1	1.000	-	-		FOG0001029
OrthoInspector	1	1.000	-	-		oto18542
orthoMCL	1	0.900	-	-		OOG6_102828
Panther	1	1.100	-	-	LDO	PTHR24031
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2082
SonicParanoid	1	1.000	-	-		X3550
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.840