Protein Alignment CNT1 and SLC28A1

DIOPT Version :10

• Sequence 1: NP_610447.2
• Gene: CNT1 / 35915
• FlyBaseID: FBgn0033371
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_011520505.1
• Gene: SLC28A1 / 9154
• HGNCID: 11001
• Length: 692
• Species: Homo sapiens
• Alignment Length: 540
• Identity: 200/540 - (37%)
• Similarity: 321/540 - (59%)
• Gaps: 44/540 - (8%)

  Fly    84 ETSEKPV-------PEVKPKLLCQ-----INW------CHGY-GFLIVLFILFY----ILWLYYW 125
            |.:.||.       |.::.:..|:     ..|      |.|. .||:|..:|.:    .|::...
Human    53 EAAPKPFSRWRNLQPALRARSFCREHMQLFRWIGTGLLCTGLSAFLLVACLLDFQRALALFVLTC 117

  Fly   126 VFKPFVGIKLYNNYLEPVIDKWIAFSRQ-----WIVSGVMLAIVLAVVVAYLGFECRNDAYKAIG 185
            |...|:|.:|....|.|.:.:::.....     |...|:.||..|.:|: :|..:......:.:.
Human   118 VVLTFLGHRLLKRLLGPKLRRFLKPQGHPRLLLWFKRGLALAAFLGLVL-WLSLDTSQRPEQLVS 181

  Fly   186 LLGPVCFVLIGFAVSKHHLQVPWRIVTHGLLGQLLLGILCLRLPFGRSIFQCLGDKVTIFLNYAQ 250
            ..|...||.:.||.||||..|.||.|:.||..|.:||:|.:|...|...|:.||:::.|||:|.:
Human   182 FAGICVFVALLFACSKHHCAVSWRAVSWGLGLQFVLGLLVIRTEPGFIAFEWLGEQIRIFLSYTK 246

  Fly   251 HGARFVYGDRICDEYVFAFAILAVVFFFSVITSIMYYLGWMQFILNGFGFLLQAMVGTTVCESVN 315
            .|:.||:|:.:..: ||||.:|.::.|||.:.|::|::|.||:::....:|:|..:|||..|:::
Human   247 AGSSFVFGEALVKD-VFAFQVLPIIVFFSCVISVLYHVGLMQWVILKIAWLMQVTMGTTATETLS 310

  Fly   316 AAGNVFLSMTESPLVIRPYIEILTVSELHAICTSGYATVAGTVLGAYVSFGASASFLIAASVMAA 380
            .|||:|:|.||:||:||||:..:|:||:|.:.|.||||:||::||||:|||..|:.|||||||||
Human   311 VAGNIFVSQTEAPLLIRPYLADMTLSEVHVVMTGGYATIAGSLLGAYISFGIDATSLIAASVMAA 375

  Fly   381 PGSLAFAKLFYPETEES-LTRSDNIKLESSTDTSILDAAASGAAAALLIVLGIVSNIIAFLAIVF 444
            |.:||.:||.|||.||| ..|.:.:||......::::||::|||.::.:|..|.:|:|||||::.
Human   376 PCALALSKLVYPEVEESKFRREEGVKLTYGDAQNLIEAASTGAAISVKVVANIAANLIAFLAVLD 440

  Fly   445 FLDAVTEWIFELIGLHNITLLYILSQIFIPIVFVMGVPWHDCQAIGLVVAQKSFINEFVAYRNLG 509
            |::|...|:.:::.:..::...|.|.|..|:.|:|||.|.||..:..::..|.|:||||||::|.
Human   441 FINAALSWLGDMVDIQGLSFQLICSYILRPVAFLMGVAWEDCPVVAELLGIKLFLNEFVAYQDLS 505

  Fly   510 IL-----------VSDKK--VDPRSAAIATFALCGFANPGSLGIVIASLSAMAPSRRSDITRVAF 561
            ..           |.|:|  :..|:..:.|||||||||..|:||::..|::|.|.|:||.:::..
Human   506 KYKQRRLAGAEEWVGDRKQWISVRAEVLTTFALCGFANFSSIGIMLGGLTSMVPQRKSDFSQIVL 570

  Fly   562 RSYFAGSFVSFTSASLAGIL 581
            |:.|.|:.||..:|.:||||
Human   571 RALFTGACVSLVNACMAGIL 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CNT1	NP_610447.2	NupC	184..582	CDD:441575	174/412 (42%)
SLC28A1	XP_011520505.1	nupC	179..590	CDD:273278	172/411 (42%)