Protein Alignment CNT1 and slc28a1

DIOPT Version :9

• Sequence 1: NP_610447.2
• Gene: CNT1 / 35915
• FlyBaseID: FBgn0033371
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_005159357.1
• Gene: slc28a1 / 571287
• ZFINID: ZDB-GENE-050419-117
• Length: 654
• Species: Danio rerio
• Alignment Length: 599
• Identity: 210/599 - (35%)
• Similarity: 329/599 - (54%)
• Gaps: 82/599 - (13%)

  Fly    50 KDSKECWPNRGSEATTESIDNST---EDDDDDDY-DTEETSEKPVPEVKPKLLCQINWC------ 104
            ||.::......|....:.:||..   ||...||. |:::.|||.....|....|....|
Zfish     2 KDKEDLQLTDVSYGNEQGVDNPVFVKEDTLPDDLSDSDKESEKDSKSEKESSSCMSKACLPITVT 66

  Fly   105 ------HGYGFLIVLFILFYIL---WLYYWVFKPFVGI-------------------KLYNNY-- 139
                  |.   .|:.:|:..||   :|.|:::..::..                   :|...|
Zfish    67 ETFFKTHS---KIIKYIVLAILAAGYLAYFIYACYLSFQRALALVVLTCLGVFILVCELVFRYKG 128

  Fly   140 ------LEPVID------KWIAFSRQWIVSGVMLAIVLAVVVAYLGFECRNDAYKAIGLLGPVCF 192
                  .:||..      ||:    :|    |.:.||:.::||:|..:.|....:.|...|...|
Zfish   129 DSIKRCFKPVQRCFRSNMKWM----KW----VFIVIVVGLLVAWLAVDTRKRPEQLISFGGVCLF 185

  Fly   193 VLIGFAVSKHHLQVPWRIVTHGLLGQLLLGILCLRLPFGRSIFQCLGDKVTIFLNYAQHGARFVY 257
            ::..|..|.|...|.|..|..||..|..:|:..:|...|...|:.||.:|.|||:|.:.|:.||:
Zfish   186 IVAIFLFSAHRTAVRWSTVFWGLGLQFAIGLFVIRTEPGLVAFEWLGKQVQIFLDYTKAGSGFVF 250

  Fly   258 GDRICDEYVFAFAILAVVFFFSVITSIMYYLGWMQFILNGFGFLLQAMVGTTVCESVNAAGNVFL 322
            |:.|  :.:|||..|.:|.|||.:.|::||||.||:::....:::|..:||:..|:::.|||:|:
Zfish   251 GNLI--DNIFAFQALPIVVFFSSVMSVLYYLGVMQWVITKISWVMQVTMGTSSTETLSVAGNIFV 313

  Fly   323 SMTESPLVIRPYIEILTVSELHAICTSGYATVAGTVLGAYVSFGASASFLIAASVMAAPGSLAFA 387
            ..||:||:||||::.:|.||:||:.|.|:||:||:|:||::|||..||.||:|||||||.:||.:
Zfish   314 GQTEAPLLIRPYLKDMTKSEIHAVMTGGFATIAGSVMGAFISFGIDASSLISASVMAAPCALAIS 378

  Fly   388 KLFYPETEES-LTRSDNIKLESSTDTSILDAAASGAAAALLIVLGIVSNIIAFLAIVFFLDAVTE 451
            ||.|||||:| .|....||::|..:.::|:|.:.||:|::.:|..|.:|:||||||:.|::|...
Zfish   379 KLSYPETEKSKFTSKSQIKVDSGGEQNVLEAVSGGASASIGLVANIAANLIAFLAILGFINATLR 443

  Fly   452 WIFELIGLHNITLLYILSQIFIPIVFVMGVPWHDCQAIGLVVAQKSFINEFVAYRNL-------- 508
            |:..::|..::|...|.|.:|:|:.|:||:|:.:...:..::..|.|:|||:||..|
Zfish   444 WLGGMVGYPDVTFELICSFVFMPVAFMMGIPYDESFKVAELIGTKLFLNEFIAYEKLSELKNNRL 508

  Fly   509 -GILVSDKKVDP-----RSAAIATFALCGFANPGSLGIVIASLSAMAPSRRSDITRVAFRSYFAG 567
             |||  |...||     ||..|.|:|||||||..||||||..||::.|.::..|:.:..|:.|.|
Zfish   509 NGIL--DDNGDPNWISVRSEIICTYALCGFANFSSLGIVIGGLSSICPPKKGVISSLVLRALFTG 571

  Fly   568 SFVSFTSASLAGIL 581
            :.||..:|.:||||
Zfish   572 TCVSLINACIAGIL 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CNT1	NP_610447.2	nupC	184..581	CDD:273278	171/411 (42%)
		Nucleos_tra2_N	188..257	CDD:280026	24/68 (35%)
		Gate	271..366	CDD:284976	43/94 (46%)
		Nucleos_tra2_C	372..581	CDD:284970	93/223 (42%)
slc28a1	XP_005159357.1	nupC	176..585	CDD:273278	171/412 (42%)
		Nucleos_tra2_N	181..250	CDD:280026	24/68 (35%)
		Gate	261..357	CDD:284976	43/95 (45%)
		Nucleos_tra2_C	363..585	CDD:284970	93/223 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592666
Domainoid	1	1.000	123	1.000	Domainoid score	I5542
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H20891
Inparanoid	1	1.050	324	1.000	Inparanoid score	I2475
OMA	1	1.010	-	-		QHG63093
OrthoDB	1	1.010	-	-		D251221at33208
OrthoFinder	1	1.000	-	-		FOG0001233
OrthoInspector	1	1.000	-	-		otm25845
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10590
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X691
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	12.010