Protein Alignment CNT1 and Slc28a1

DIOPT Version :10

• Sequence 1: NP_610447.2
• Gene: CNT1 / 35915
• FlyBaseID: FBgn0033371
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_446315.1
• Gene: Slc28a1 / 116642
• RGDID: 621223
• Length: 648
• Species: Rattus norvegicus
• Alignment Length: 535
• Identity: 198/535 - (37%)
• Similarity: 318/535 - (59%)
• Gaps: 55/535 - (10%)

  Fly    91 PEVKPKLLCQ-----INW-CHG------YGFLIVLFIL-------------FYILWLYYWVFKPF 130
            |.|:.:..|:     ..| |.|      .|||:|..:|             ..:::|.|.:.|..
  Rat    67 PTVQARSFCREHRQLFGWICKGLLSTACLGFLMVACLLDLQRALALLIITCVVLVFLAYDLLKRL 131

  Fly   131 VGIKLYNNYLEPVIDKWIAFSRQ-----WIVSGVMLAIVLAVVVAYLGFECRNDAYKAIGLLGPV 190
            :|.||         .:.:.|...     |:..|:.||..:.::: :|..:......:.:...|..
  Rat   132 LGSKL---------RRCVKFQGHSCLSLWLKRGLALAAGVGLIL-WLSLDTAQRPEQLVSFAGIC 186

  Fly   191 CFVLIGFAVSKHHLQVPWRIVTHGLLGQLLLGILCLRLPFGRSIFQCLGDKVTIFLNYAQHGARF 255
            .|:::.||.||||..|.||.|:.||..|.:||:..:|...|...||.|||::.:||:|.:.|:.|
  Rat   187 VFLVLLFAGSKHHRAVSWRAVSWGLGLQFVLGLFVIRTEPGFIAFQWLGDQIQVFLSYTEAGSSF 251

  Fly   256 VYGDRICDEYVFAFAILAVVFFFSVITSIMYYLGWMQFILNGFGFLLQAMVGTTVCESVNAAGNV 320
            |:|:.:..: ||||.:|.::.|||.:.|::||||.||:::....:|:|..:||:..|:::.|||:
  Rat   252 VFGEALVKD-VFAFQVLPIIIFFSCVMSVLYYLGLMQWVILKIAWLMQVTMGTSATETLSVAGNI 315

  Fly   321 FLSMTESPLVIRPYIEILTVSELHAICTSGYATVAGTVLGAYVSFGASASFLIAASVMAAPGSLA 385
            |:|.||:||:||||:..:|:||:|.:.|.||||:||::||||:|||..|:.||||||||||.:||
  Rat   316 FVSQTEAPLLIRPYLADMTLSEVHVVMTGGYATIAGSLLGAYISFGIDAASLIAASVMAAPCALA 380

  Fly   386 FAKLFYPETEESLTRSDN-IKLESSTDTSILDAAASGAAAALLIVLGIVSNIIAFLAIVFFLDAV 449
            .:||.|||.|||..||:| :||......::|:||::|||.::.:|..|.:|:|||||::.|::|.
  Rat   381 LSKLVYPEVEESKFRSENGVKLTYGDAQNLLEAASAGAAISVKVVANIAANLIAFLAVLAFVNAA 445

  Fly   450 TEWIFELIGLHNITLLYILSQIFIPIVFVMGVPWHDCQAIGLVVAQKSFINEFVAYRNLGIL--- 511
            ..|:.:::.:..::...|.|.:..|:.|:|||.|.||..:..::..|.|:||||||:.|...
  Rat   446 LSWLGDMVDIQGLSFQLICSYVLRPVAFLMGVAWEDCPVVAELLGIKFFLNEFVAYQELSQYKQR 510

  Fly   512 --------VSDKK--VDPRSAAIATFALCGFANPGSLGIVIASLSAMAPSRRSDITRVAFRSYFA 566
                    :.|||  :..|:..:.|:|||||||..|:||::..|:::.|.||||.:::..|:...
  Rat   511 RLAGAEEWLGDKKQWISVRAEILTTYALCGFANFSSIGIMLGGLTSLVPQRRSDFSQIVLRALIT 575

  Fly   567 GSFVSFTSASLAGIL 581
            |:|||..:|.:||||
  Rat   576 GAFVSLLNACVAGIL 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CNT1	NP_610447.2	NupC	184..582	CDD:441575	175/412 (42%)
Slc28a1	NP_446315.1	nupC	179..590	CDD:273278	173/411 (42%)