Protein Alignment CNT1 and slc28a2

DIOPT Version :9

• Sequence 1: NP_610447.2
• Gene: CNT1 / 35915
• FlyBaseID: FBgn0033371
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_002934615.3
• Gene: slc28a2 / 100496776
• XenbaseID: XB-GENE-965932
• Length: 647
• Species: Xenopus tropicalis
• Alignment Length: 587
• Identity: 214/587 - (36%)
• Similarity: 329/587 - (56%)
• Gaps: 80/587 - (13%)

  Fly    72 TEDD--DDDDYDT--EETSEKPVPEVKPKL----------------------------------- 97
            :||:  .:|||..  |...|.|..:|..|:
 Frog    14 SEDETASNDDYSVVIEAPPENPKTDVWSKVSKPFDASEKFIKKHRNILKYIVIGILCAGFAAYFI 78

  Fly    98 -LCQINWCHGYGFLIVLFILFYILWLYYWVFKPFVGIKLYNNYLEPV------IDKWIAFSRQWI 155
             .|.:|:......:::..::.:  :|.|.:.|...| |....:|.||      ..||:    :|
 Frog    79 AACVLNFNRAVALVVITCVVLF--FLGYDLVKKLYG-KHIMRFLRPVGSCLKKNKKWL----KW- 135

  Fly   156 VSGVMLAIVLAVVVAYLGFECRNDAYKAIGLLGPVCFVLIGFAVSKHHLQVPWRIVTHGLLGQLL 220
               |...:|||.::|:|..:......:.|...|...|:||.|.:||||..|.||.|..||..:.:
 Frog   136 ---VFCILVLAGLIAWLVIDTSKRPEQLISFGGVCMFILILFVLSKHHRAVSWRAVFWGLGLEFV 197

  Fly   221 LGILCLRLPFGRSIFQCLGDKVTIFLNYAQHGARFVYGDRICDEYVFAFAILAVVFFFSVITSIM 285
            |||..:|...|...|:.:|:::.|||||...|:.||:|..:..: ||||..|.:|.|||.:.|::
 Frog   198 LGIFIIRTEPGYQAFKFVGEQIQIFLNYTTAGSGFVFGTALIQD-VFAFQALPIVVFFSCVMSVL 261

  Fly   286 YYLGWMQFILNGFGFLLQAMVGTTVCESVNAAGNVFLSMTESPLVIRPYIEILTVSELHAICTSG 350
            ||:|.||:::....:|:|..:|||..||::.|||:|:..||:||:||||:..:|.||:||:.|.|
 Frog   262 YYVGLMQYVILKISWLMQITMGTTATESLSVAGNIFVGQTEAPLLIRPYLPDMTKSEIHAVMTGG 326

  Fly   351 YATVAGTVLGAYVSFGASASFLIAASVMAAPGSLAFAKLFYPETEES-LTRSDNIKLESSTDTSI 414
            :.|:||:|||||:|||..||.||||||||||.:||.:||.||||||| ....:.:.:|...:.::
 Frog   327 FGTIAGSVLGAYISFGIDASSLIAASVMAAPCALALSKLVYPETEESKFKNEEGVIIEKGEERNV 391

  Fly   415 LDAAASGAAAALLIVLGIVSNIIAFLAIVFFLDAVTEWIFELIGLHNITLLYILSQIFIPIVFVM 479
            |:||::||:|::.:|..|.:|:|||:|::.|::|...|:..::....:||..|||.||:||.|:|
 Frog   392 LEAASNGASASVGLVANIAANLIAFMALLEFINAAFSWLGGMVNYPKLTLQLILSYIFMPIAFMM 456

  Fly   480 GVPWHDCQAIGLVVAQKSFINEFVAYR------NLGILVSDKKVD-------PRSAAIATFALCG 531
            ||.|.:...:|.::..|..:|||||||      ||.:..:::.:|       .|:..|.|:||||
 Frog   457 GVRWDEADKVGEMLGTKIILNEFVAYRQLAEYKNLRLSGTEEWIDGQRQWISERAEVITTYALCG 521

  Fly   532 FANPGSLGIVIASLSAMAPSRRSDITRVAFRSYFAGSFVSFTSASLAGIL-----IQN---EYTG 588
            |||..|:||::..||:||..|:.|:.:|..|:...|:.|||.:|.:||||     |:|   ..|.
 Frog   522 FANFSSIGIMLGGLSSMATERKGDLAKVVLRALLTGACVSFVNACVAGILFSPRVIENCKDLLTS 586

  Fly   589 GN 590
            ||
 Frog   587 GN 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CNT1	NP_610447.2	nupC	184..581	CDD:273278	178/410 (43%)
		Nucleos_tra2_N	188..257	CDD:280026	29/68 (43%)
		Gate	271..366	CDD:284976	46/94 (49%)
		Nucleos_tra2_C	372..581	CDD:284970	92/222 (41%)
slc28a2	XP_002934615.3	nupC	160..571	CDD:273278	178/411 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	187	1.000	Domainoid score	I3281
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H20891
Inparanoid	1	1.050	382	1.000	Inparanoid score	I2007
OMA	1	1.010	-	-		QHG63093
OrthoDB	1	1.010	-	-		D251221at33208
OrthoFinder	1	1.000	-	-		FOG0001233
OrthoInspector	1	1.000	-	-		mtm9539
Panther	1	1.100	-	-	O	PTHR10590
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X691
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080