Protein Alignment CNT2 and Slc28a2

DIOPT Version :9

• Sequence 1: NP_610446.1
• Gene: CNT2 / 35914
• FlyBaseID: FBgn0025709
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_001343461.1
• Gene: Slc28a2 / 269346
• MGIID: 1913105
• Length: 660
• Species: Mus musculus
• Alignment Length: 624
• Identity: 230/624 - (36%)
• Similarity: 342/624 - (54%)
• Gaps: 87/624 - (13%)

  Fly     4 ESSKG------------AINNGYEL-DHKELDIR-DSEEFTE-HPLDD------------TSEVA 41
            |.|||            ..|.|.|| :...|:.| ..||.|: |.|:|            .....
Mouse     2 EKSKGRKSVSQATVENCMENPGLELMEGGNLEQRYTQEEVTQGHSLEDGLGHSSLWSRRIFQPFT 66

  Fly    42 NKKGYFEKNPKVARLVRISIYVLLHLCVVGYFSYATYHYHDITNYECYWKDNPLCGINFCTGYGM 106
            ..:.:||::   |.|.|..:..||.|....||..|                   |.:||.....:
Mouse    67 KARSFFERH---AGLFRKILLGLLCLAYAAYFLAA-------------------CILNFQRALAL 109

  Fly   107 LLLLLGFIYLGLFYYYVFKPMVGHSLHRNY-------IKPFSKKWHNFSRTRV-VSLASIALLLA 163
            .::....|::          :..|.|.:.:       :||......|....|| |.|:.:.|:|
Mouse   110 FVITCLVIFI----------LACHFLKKFFPKEQLRCLKPLENTHLNLWAKRVFVGLSVVGLIL- 163

  Fly   164 LLAIFVYFECRDETQKLVSLVAPCFFILCGYVFSTNRRAINWRIVITGITCQFLLGIFCIRWEVG 228
                ::..:.....::|:|....|.|||..:..|.:..|:.||.|..|:..||:.||..||.|.|
Mouse   164 ----WLALDTAQRPEQLISFAGICMFILILFACSKHHSAVCWRTVFWGLGLQFIFGILVIRTEPG 224

  Fly   229 RKIFECLGNKVATFLGYATDGAEFVFGDFLVNNNVFAFAILPVIFFFSFFISILYYMGTMQWVVI 293
            ...|:.||:::..||.|..:|:.|||||.|| .|||||..||:|.||...:|||||:|.:|||:.
Mouse   225 FNAFQWLGDQIQIFLAYTVEGSSFVFGDTLV-QNVFAFQSLPIIIFFGCVMSILYYLGLVQWVIQ 288

  Fly   294 KLGWILQQILGTTVCESVTAAANIFLGMSESPLLIRPYINKLTKSEIHSIMVSGFATVSGTVLAA 358
            |:.|.||..:|||..|::..|.|||:||:|:|||||||:..:|.||||::|..||||::||||.|
Mouse   289 KVAWFLQITMGTTAAETLAVAGNIFVGMTEAPLLIRPYLADMTISEIHAVMTGGFATIAGTVLGA 353

  Fly   359 YLSFGASAAHLITSSVMAAPATLAISKLYMPETEESQ-TSSDSIELEKSQDSSLLDAASSGASNA 422
            ::|||..|:.||::||||||..||:|||..||.|||: .|.:.::|.:.::.::|:|||:||::|
Mouse   354 FISFGIDASSLISASVMAAPCALALSKLVYPEVEESKFKSKEGLKLPRGEERNILEAASNGATDA 418

  Fly   423 VPIVLGIIANIVAFVAFIAFLNGLVSWFGYLVGLEQIDFEWIFSKLFIPLVWAMGVPKEDCDIIA 487
            :.:|..:.||::||:|.:||:|..:||.|.:|.:..:.|:.|.|.:..|:|:.|||...||.::|
Mouse   419 ISLVANVAANLIAFLAVLAFINATLSWLGEMVDIHGLSFQVICSYVLRPMVFMMGVQWADCPLVA 483

  Fly   488 KVVATKTIINEFVAYERLGQYI-------------ENNDITARSAGIATFAICGFANPSSLGILI 539
            ::|..|..|||||||::|.||.             |...|:.::..|.||::|||||.||:||.:
Mouse   484 EIVGVKFFINEFVAYQQLSQYKNKRLSGVEEWINGEKQWISVKAEIITTFSLCGFANLSSIGITL 548

  Fly   540 GSLSAMAPHRRSTITAVAFRAFVVGSIVCFVSASFAGIL 578
            |.|::|.|.|:|.:..:..||...|:.|.|:||..||||
Mouse   549 GGLTSMIPQRKSDLCKIVVRALFTGACVSFISACMAGIL 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CNT2	NP_610446.1	nupC	180..578	CDD:273278	186/411 (45%)
		Nucleos_tra2_N	187..254	CDD:280026	26/66 (39%)
		Gate	268..363	CDD:284976	52/94 (55%)
		Nucleos_tra2_C	368..578	CDD:284970	92/223 (41%)
Slc28a2	NP_001343461.1	nupC	176..587	CDD:273278	186/411 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847402
Domainoid	1	1.000	190	1.000	Domainoid score	I3256
eggNOG	1	0.900	-	-		E1_COG1972
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	376	1.000	Inparanoid score	I2058
Isobase	1	0.950	-	0	Normalized mean entropy	S5202
OMA	1	1.010	-	-		QHG63093
OrthoDB	1	1.010	-	-		D251221at33208
OrthoFinder	1	1.000	-	-		FOG0001233
OrthoInspector	1	1.000	-	-		mtm8877
orthoMCL	1	0.900	-	-		OOG6_102197
Panther	1	1.100	-	-	O	PTHR10590
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4851
SonicParanoid	1	1.000	-	-		X691
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.750