Protein Alignment CNT2 and slc-28.1

DIOPT Version :10

• Sequence 1: NP_610446.1
• Gene: CNT2 / 35914
• FlyBaseID: FBgn0025709
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_503967.1
• Gene: slc-28.1 / 178770
• WormBaseID: WBGene00017867
• Length: 568
• Species: Caenorhabditis elegans
• Alignment Length: 569
• Identity: 180/569 - (31%)
• Similarity: 292/569 - (51%)
• Gaps: 47/569 - (8%)

  Fly    40 VANKKGYFEKNPKVARLVRISIYVLLHLCVVGYFSYATYHYHDITNYE-CYWKDNPLCG----IN 99
            |.|||.:..|...:..:.:.|:                  .|:...|: .|.|..|..|    :.
 Worm     2 VLNKKVHQNKEKNLISVTKSSL------------------EHNANFYQRIYQKICPFIGPAAIVA 48

  Fly   100 FCTGYGMLLLLLG---------FIYLGLFYY--YVFKPMVGHSLHRNYIKPFSKKWHNFSRTRVV 153
            |...|...|:..|         .||:.||::  :|...:||....:.....|:.|.::|::.|
 Worm    49 FLLVYHGYLIAAGIHNYQKASPLIYVTLFFWLCFVINFIVGTKNFKVVYADFAGKLNDFAKRR-- 111

  Fly   154 SLASIALLLALL-AIFVY--FECRDETQKLVSLVAPCFFILCGYVFSTNRRAINWRIVITGITCQ 215
            :...|...||.. |:|.|  .|...|..:|.......||::...|||...|.|||.||.:.:...
 Worm   112 AFVPITFKLAFAGALFAYTIVESLSEPTRLTGFGGYVFFVIFMVVFSNRPRKINWNIVTSALIFH 176

  Fly   216 FLLGIFCIRWEVGRKIFECLGNKVATFLGYATDGAEFVFGDFLVNNN------VFAFAILPVIFF 274
            :.|.:..::|..||..|:.|...:...|.||..||:||||......|      ||.|..|..:.:
 Worm   177 YCLALIVLKWPTGRWFFDQLSQLIIGLLEYAQVGAKFVFGFIAGPPNICDLAPVFIFTSLQTLIY 241

  Fly   275 FSFFISILYYMGTMQWVVIKLGWILQQILGTTVCESVTAAANIFLGMSESPLLIRPYINKLTKSE 339
            ||..:::|:|.|.:|..:.|..|.::.::|||..|||.:.|..|||.:|:||:|:||:.|||.||
 Worm   242 FSAVVALLFYFGIIQIALKKSTWFMKVLIGTTPVESVYSWACTFLGQTEAPLVIKPYLEKLTDSE 306

  Fly   340 IHSIMVSGFATVSGTVLAAYLSFGASAAHLITSSVMAAPATLAISKLYMPETEESQTSSDSIELE 404
            :.:::.|||:...|||.|||::.||....::|:|:::||.:||.|||..||.:|:....:..||:
 Worm   307 LFAVLTSGFSCTGGTVFAAYVALGACPESILTASILSAPMSLACSKLMYPEEQETIIKEEDFELD 371

  Fly   405 KSQDSSLLDAASSGASNAVPIVLGIIANIVAFVAFIAFLNGLVSWFGYLVGLEQIDFEWIFSKLF 469
            ...:....|...|.....||.|..|.|.:|..::.:|.|:.:..:.|.|:|.:...|:.:|...|
 Worm   372 HENEKGFFDTLCSAGVALVPTVFAIGATLVVVMSLLALLDQIFFYIGDLIGYDGWSFQMLFGYAF 436

  Fly   470 IPLVWAMGVPKEDCD--IIAKVVATKTIINEFVAYERLGQYIENNDITARSAGIATFAICGFANP 532
            .||.:.||:......  ::|:::.:||.:||||||::|||..:...:..:|..:||:|:|||:|.
 Worm   437 FPLAYIMGITNNSNQTLLVAQLMGSKTAVNEFVAYDKLGQLQKEGKLDPKSVLVATYALCGFSNF 501

  Fly   533 SSLGILIGSLSAMAPHRRSTITAVAFRAFVVGSIVCFVSASFAGILIQE 581
            .|:||.:..:..:||.|::..:.|..||...|:|.||::|:.|||||.:
 Worm   502 GSMGIQMEVIGGLAPGRKTVASKVMLRALCAGAIACFMNATVAGILISD 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CNT2	NP_610446.1	NupC	180..579	CDD:441575	143/406 (35%)
slc-28.1	NP_503967.1	nupC	141..547	CDD:273278	142/405 (35%)