Protein Alignment CNT2 and Slc28a1

DIOPT Version :10

• Sequence 1: NP_610446.1
• Gene: CNT2 / 35914
• FlyBaseID: FBgn0025709
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_446315.1
• Gene: Slc28a1 / 116642
• RGDID: 621223
• Length: 648
• Species: Rattus norvegicus
• Alignment Length: 504
• Identity: 196/504 - (38%)
• Similarity: 309/504 - (61%)
• Gaps: 33/504 - (6%)

  Fly   101 CTGYGML-----------LLLLGFIYLGLFYYYVFKPMVGHSLHRNYIKPFSKKWHNFSRTRVVS 154
            |.|:.|:           ||::..:.|....|.:.|.::|..|.|      ..|:...|...:..
  Rat    94 CLGFLMVACLLDLQRALALLIITCVVLVFLAYDLLKRLLGSKLRR------CVKFQGHSCLSLWL 152

  Fly   155 LASIALLLAL-LAIFVYFECRDETQKLVSLVAPCFFILCGYVFSTNRRAINWRIVITGITCQFLL 218
            ...:||...: |.:::..:.....::|||....|.|::..:..|.:.||::||.|..|:..||:|
  Rat   153 KRGLALAAGVGLILWLSLDTAQRPEQLVSFAGICVFLVLLFAGSKHHRAVSWRAVSWGLGLQFVL 217

  Fly   219 GIFCIRWEVGRKIFECLGNKVATFLGYATDGAEFVFGDFLVNNNVFAFAILPVIFFFSFFISILY 283
            |:|.||.|.|...|:.||:::..||.|...|:.||||:.|| .:||||.:||:|.|||..:|:||
  Rat   218 GLFVIRTEPGFIAFQWLGDQIQVFLSYTEAGSSFVFGEALV-KDVFAFQVLPIIIFFSCVMSVLY 281

  Fly   284 YMGTMQWVVIKLGWILQQILGTTVCESVTAAANIFLGMSESPLLIRPYINKLTKSEIHSIMVSGF 348
            |:|.||||::|:.|::|..:||:..|:::.|.|||:..:|:|||||||:..:|.||:|.:|..|:
  Rat   282 YLGLMQWVILKIAWLMQVTMGTSATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEVHVVMTGGY 346

  Fly   349 ATVSGTVLAAYLSFGASAAHLITSSVMAAPATLAISKLYMPETEESQ-TSSDSIELEKSQDSSLL 412
            ||::|::|.||:|||..||.||.:||||||..||:|||..||.|||: .|.:.::|......:||
  Rat   347 ATIAGSLLGAYISFGIDAASLIAASVMAAPCALALSKLVYPEVEESKFRSENGVKLTYGDAQNLL 411

  Fly   413 DAASSGASNAVPIVLGIIANIVAFVAFIAFLNGLVSWFGYLVGLEQIDFEWIFSKLFIPLVWAMG 477
            :|||:||:.:|.:|..|.||::||:|.:||:|..:||.|.:|.::.:.|:.|.|.:..|:.:.||
  Rat   412 EAASAGAAISVKVVANIAANLIAFLAVLAFVNAALSWLGDMVDIQGLSFQLICSYVLRPVAFLMG 476

  Fly   478 VPKEDCDIIAKVVATKTIINEFVAYERLGQYIEN---------ND----ITARSAGIATFAICGF 529
            |..|||.::|:::..|..:||||||:.|.||.:.         .|    |:.|:..:.|:|:|||
  Rat   477 VAWEDCPVVAELLGIKFFLNEFVAYQELSQYKQRRLAGAEEWLGDKKQWISVRAEILTTYALCGF 541

  Fly   530 ANPSSLGILIGSLSAMAPHRRSTITAVAFRAFVVGSIVCFVSASFAGIL 578
            ||.||:||::|.|:::.|.|||..:.:..||.:.|:.|..::|..||||
  Rat   542 ANFSSIGIMLGGLTSLVPQRRSDFSQIVLRALITGAFVSLLNACVAGIL 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CNT2	NP_610446.1	NupC	180..579	CDD:441575	180/413 (44%)
Slc28a1	NP_446315.1	nupC	179..590	CDD:273278	178/411 (43%)