DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8197 and emb2004

DIOPT Version :9

Sequence 1:	NP_001286225.1	Gene:	CG8197 / 35912	FlyBaseID:	FBgn0033369	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_563871.1	Gene:	emb2004 / 837591	AraportID:	AT1G10510	Length:	605	Species:	Arabidopsis thaliana

Alignment Length:	251	Identity:	62/251 - (24%)
Similarity:	114/251 - (45%)	Gaps:	17/251 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 VMLRLNAAKMNVSQLSLEGTPLTDEDVRILREFLLVSKTLRRLNVSSCSLTQFNFALIADGVYKS 187
            :||::         |:|.|.|:.||..:.|...|:.:.::..|.::|..:.......||:.:.::
plant   226 IMLKI---------LNLSGNPIGDEGAKTLCATLMENSSIEILQLNSTDIGDEGAKEIAELLKRN 281

  Fly   188 PGVRRLSANRLLGMSLSLDTEKISSVLSSLLMQNTLWALSLEHCELTAQDMIPIAEHLARTNSKF 252
            ..:|.:..|..:     :|....:|:..:||..||:..|.|......|.....:|:.| ..|...
plant   282 STLRIIELNNNM-----IDYSGFTSLAGALLENNTIRNLHLNGNYGGALGANALAKGL-EGNKSL 340

  Fly   253 RRLRIACNKIGPDGAFFLLRGMSM-GGNLELLDLSYCSIGTHGGEWVAKYLASCRRLQVLHLNYN 316
            |.|.:..|.||.:|...|:.|:|. .|.:.||||...||...|..:||:|:...:.|..|:|..|
plant   341 RELHLHGNSIGDEGTRALMAGLSSHKGKVALLDLGNNSISAKGAFYVAEYIKRSKSLVWLNLYMN 405

  Fly   317 DMGPTAVNLILLAMKKQCKLEKLTLYGNHFDSRTAMIVRRLLDAEVVLHSELDISY 372
            |:|......|..::|:...:..:.|.||:..:.....:.:.|....:: :.|::.|
plant   406 DIGDEGAEKIADSLKQNRSIATIDLGGNNIHAEGVNAIAQALKDNAII-TTLEVGY 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8197	NP_001286225.1	leucine-rich repeat	134..161	CDD:275381	8/26 (31%)
		LRR_RI	137..374	CDD:238064	60/237 (25%)
		leucine-rich repeat	162..189	CDD:275381	4/26 (15%)
		leucine-rich repeat	202..220	CDD:275380	4/17 (24%)
		leucine-rich repeat	223..251	CDD:275380	6/27 (22%)
		leucine-rich repeat	252..279	CDD:275380	9/27 (33%)
		leucine-rich repeat	280..307	CDD:275380	10/26 (38%)
		leucine-rich repeat	308..335	CDD:275380	8/26 (31%)
		leucine-rich repeat	336..357	CDD:275380	3/20 (15%)
emb2004	NP_563871.1	LRR_RI	160..423	CDD:423007	56/211 (27%)
		leucine-rich repeat	173..193	CDD:275380
		leucine-rich repeat	194..221	CDD:275380
		leucine-rich repeat	228..249	CDD:275380	8/29 (28%)
		leucine-rich repeat	250..279	CDD:275380	5/28 (18%)
		leucine-rich repeat	284..311	CDD:275380	6/31 (19%)
		leucine-rich repeat	312..339	CDD:275380	6/27 (22%)
		LRR_RI	315..577	CDD:423007	40/148 (27%)
		leucine-rich repeat	340..368	CDD:275380	9/27 (33%)
		leucine-rich repeat	369..396	CDD:275380	10/26 (38%)
		leucine-rich repeat	425..448	CDD:275380	3/22 (14%)
		leucine-rich repeat	453..480	CDD:275380	2/9 (22%)
		leucine-rich repeat	509..537	CDD:275381
		leucine-rich repeat	538..561	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4308
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810