DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8197 and si:ch211-108d22.2

DIOPT Version :9

Sequence 1:	NP_001286225.1	Gene:	CG8197 / 35912	FlyBaseID:	FBgn0033369	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	XP_009297512.1	Gene:	si:ch211-108d22.2 / 793004	ZFINID:	ZDB-GENE-131127-97	Length:	1739	Species:	Danio rerio

Alignment Length:	185	Identity:	40/185 - (21%)
Similarity:	63/185 - (34%)	Gaps:	64/185 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 VSNWDAGLLKDFVRSL-----LP-VWYIELRLMRFPREFFVMLRLNAAKMNV------------- 134
            |.|::....:.|:.:|     :| ||.|:|. .|.......:|:|.|.|..|
Zfish  1556 VKNYETQTGRSFIPALQSVFQIPDVWIIDLS-QRKTSVLLEVLKLQAEKKPVELRGCSEEESEVK 1619

  Fly   135 ---------SQLS------------------------------LEGTPLTDEDVRILREFLLVSK 160
                     ||||                              |..|||..:..|.|...|..|:
Zfish  1620 SFLQCLPYISQLSCAKPLLLQFLTHVRREQAESLSAALGEELDLSQTPLDLQACRGLALILEYSE 1684

  Fly   161 TLRRLNVSSCSLTQFNFALIADGVYKSPGVRRLSANRLLGMSLSLDTEKISSVLS 215
            .|..|:::.|.||.::..|:...::|:..:     |........:..:||.||.|
Zfish  1685 GLTELDLNQCHLTDYSLDLLLPNLHKAQNI-----NFRWNYITDVGAQKIYSVFS 1734

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8197	NP_001286225.1	leucine-rich repeat	134..161	CDD:275381	13/78 (17%)
		LRR_RI	137..374	CDD:238064	23/109 (21%)
		leucine-rich repeat	162..189	CDD:275381	7/26 (27%)
		leucine-rich repeat	202..220	CDD:275380	5/14 (36%)
		leucine-rich repeat	223..251	CDD:275380
		leucine-rich repeat	252..279	CDD:275380
		leucine-rich repeat	280..307	CDD:275380
		leucine-rich repeat	308..335	CDD:275380
		leucine-rich repeat	336..357	CDD:275380
si:ch211-108d22.2	XP_009297512.1	CARD	12..91	CDD:260018
		P-loop_NTPase	208..352	CDD:304359
		LRR_RI	1575..>1738	CDD:238064	36/166 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900