DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG8197 and nod2

DIOPT Version :9

Sequence 1:NP_001286225.1 Gene:CG8197 / 35912 FlyBaseID:FBgn0033369 Length:387 Species:Drosophila melanogaster
Sequence 2:NP_001314973.1 Gene:nod2 / 777696 ZFINID:ZDB-GENE-061108-4 Length:980 Species:Danio rerio


Alignment Length:273 Identity:72/273 - (26%)
Similarity:110/273 - (40%) Gaps:69/273 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 LRRPQLSVQISSLVVSNWDAGLLKDFVRSLLPVWYIELRLMRFPREFFVMLRLNAAKMNVSQLSL 139
            ||:| :.:|:.:..|.  |.|     |..|||.         .|....:.||.|    |:|    
Zfish   757 LRKP-VGLQLDNNSVG--DVG-----VEQLLPC---------LPMCHSLYLRNN----NIS---- 796

  Fly   140 EGTPLTDEDVRILREFLLVSKTLRRLNVSSCSLTQFNFALIADGVYKSPGVRRLSANRLLGMSLS 204
                  ||.:|.|.|     |.:      .|.    ||..||           |..|:|      
Zfish   797 ------DEGIRKLLE-----KGI------ECE----NFQKIA-----------LFNNKL------ 823

  Fly   205 LDTEKISSVLSSLL--MQNTLWALSLEHCELTAQDMIPIAEHLARTNSKFRRLRIACNKIGPDGA 267
              |:..:...|.||  .||.| ||.|.:..:|:.....:||.|: .|...:.|.:..||:|..||
Zfish   824 --TDTCTQYFSCLLKSKQNFL-ALRLGNNNITSVGAEQLAEGLS-YNQSLQFLGLWGNKVGDRGA 884

  Fly   268 FFLLRGMSMGGNLELLDLSYCSIGTHGGEWVAKYLASCRRLQVLHLNYNDMGPTAVNLILLAMKK 332
            ..|...::....|..|.|....:|:.|...:||::...:.|:.|.||.|.:....|:.::.|:|.
Zfish   885 EVLADALTNSKTLIWLSLVDNGVGSAGACALAKFIRQNKSLEELWLNKNSICKEGVDCLIEALKM 949

  Fly   333 QCKLEKLTLYGNH 345
            ...::|:.|.||:
Zfish   950 NTSVKKVWLRGNN 962

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8197NP_001286225.1 leucine-rich repeat 134..161 CDD:275381 6/26 (23%)
LRR_RI 137..374 CDD:238064 55/211 (26%)
leucine-rich repeat 162..189 CDD:275381 5/26 (19%)
leucine-rich repeat 202..220 CDD:275380 4/19 (21%)
leucine-rich repeat 223..251 CDD:275380 9/27 (33%)
leucine-rich repeat 252..279 CDD:275380 7/26 (27%)
leucine-rich repeat 280..307 CDD:275380 7/26 (27%)
leucine-rich repeat 308..335 CDD:275380 8/26 (31%)
leucine-rich repeat 336..357 CDD:275380 4/10 (40%)
nod2NP_001314973.1 CARD_NOD2_1_CARD15 7..93 CDD:176765
CARD_NOD2_2_CARD15 114..193 CDD:260056
NACHT 271..441 CDD:283404
leucine-rich repeat 732..753 CDD:275380
LRR_RI <749..964 CDD:238064 72/273 (26%)
leucine-rich repeat 757..784 CDD:275380 11/43 (26%)
leucine-rich repeat 803..841 CDD:275380 16/71 (23%)
leucine-rich repeat 842..868 CDD:275380 9/27 (33%)
leucine-rich repeat 869..896 CDD:275380 7/26 (27%)
leucine-rich repeat 897..924 CDD:275380 7/26 (27%)
leucine-rich repeat 925..952 CDD:275380 8/26 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4308
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.