DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8197 and Nlrp14

DIOPT Version :9

Sequence 1:NP_001286225.1 Gene:CG8197 / 35912 FlyBaseID:FBgn0033369 Length:387 Species:Drosophila melanogaster
Sequence 2:NP_001002894.2 Gene:Nlrp14 / 76858 MGIID:1924108 Length:993 Species:Mus musculus


Alignment Length:246 Identity:65/246 - (26%)
Similarity:110/246 - (44%) Gaps:42/246 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   124 MLRLNAAKMNVSQ----------------LSLEGTPLTDEDVRILREFL-LVSKTLRRLNVSSCS 171
            :|||.:..:||::                |:|....|:::.|:.|.|.| ..:.:|.||.::||.
Mouse   663 VLRLASCDLNVARCQKLSNALQTNRSLVFLNLSLNNLSNDGVKSLCEVLENPNSSLERLALASCG 727

  Fly   172 LTQFNFALIADGVYKSPGVRRLSANRLLGMSLS---LDTEKISSVLSSLLM--QNTLWALSLEHC 231
            ||:....:::..:.||        .||..:.||   |:.|.| .:||..|.  |.||.:|.|..|
Mouse   728 LTKAGCKVLSSALTKS--------KRLTHLCLSDNVLEDEGI-KLLSHTLKHPQCTLQSLVLRSC 783

  Fly   232 ELTAQDMIPI-AEHLART---NSKFRRLRIACNKIGPDGAFFLLRGMSMGG-NLELLDLSYCSIG 291
            ..|     || :|||:..   |.....|.:..||:..:|...|...:.... ||:.|:|..|.:.
Mouse   784 SFT-----PIGSEHLSTALLHNRSLVHLDLGQNKLADNGVKLLCHSLQQPHCNLQELELMSCVLT 843

  Fly   292 THGGEWVAKYLASCRRLQVLHLNYNDMGPTAVNLILLAMKK-QCKLEKLTL 341
            :.....:|..|.:...|..|.|.:|.:....:|::..|::. .|.:::|.|
Mouse   844 SKACGDLASVLVNNSNLWSLDLGHNILDDAGLNILCDALRNPNCHVQRLGL 894

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8197NP_001286225.1 leucine-rich repeat 134..161 CDD:275381 8/43 (19%)
LRR_RI 137..374 CDD:238064 60/217 (28%)
leucine-rich repeat 162..189 CDD:275381 9/26 (35%)
leucine-rich repeat 202..220 CDD:275380 8/22 (36%)
leucine-rich repeat 223..251 CDD:275380 11/31 (35%)
leucine-rich repeat 252..279 CDD:275380 5/27 (19%)
leucine-rich repeat 280..307 CDD:275380 6/26 (23%)
leucine-rich repeat 308..335 CDD:275380 6/27 (22%)
leucine-rich repeat 336..357 CDD:275380 2/6 (33%)
Nlrp14NP_001002894.2 NACHT 82..249 CDD:368582
NOD2_WH 326..381 CDD:375327
NLRC4_HD2 383..500 CDD:375325
LRR_RI 635..952 CDD:393385 65/246 (26%)
LRR 1 636..657
leucine-rich repeat 637..660 CDD:275380
LRR 2 660..680 5/16 (31%)
leucine-rich repeat 661..717 CDD:275380 12/53 (23%)
LRR 3 688..708 4/19 (21%)
LRR 4 717..738 7/20 (35%)
leucine-rich repeat 718..745 CDD:275380 9/34 (26%)
LRR 5 745..765 7/20 (35%)
leucine-rich repeat 746..774 CDD:275380 10/28 (36%)
LRR 6 774..795 11/25 (44%)
leucine-rich repeat 775..802 CDD:275380 11/31 (35%)
LRR 7 802..822 4/19 (21%)
leucine-rich repeat 803..831 CDD:275380 5/27 (19%)
LRR 8 831..852 5/20 (25%)
leucine-rich repeat 832..859 CDD:275380 6/26 (23%)
LRR 9 859..879 5/19 (26%)
leucine-rich repeat 860..888 CDD:275380 6/27 (22%)
leucine-rich repeat 889..909 CDD:275380 2/6 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000189
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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