DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8197 and Lrrc74b

DIOPT Version :9

Sequence 1:NP_001286225.1 Gene:CG8197 / 35912 FlyBaseID:FBgn0033369 Length:387 Species:Drosophila melanogaster
Sequence 2:NP_083329.2 Gene:Lrrc74b / 74685 MGIID:1921935 Length:391 Species:Mus musculus


Alignment Length:228 Identity:59/228 - (25%)
Similarity:95/228 - (41%) Gaps:46/228 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   178 ALIADGVYKSPGVRRLSANRLLGMSLSLDTEKISSV--LSSLLMQNTLWALSLEHCELTAQDMIP 240
            ||.|:|.: ..|.|.::       :|.|.:.:.:||  :|.||.|.....|:|.|..|..|.:..
Mouse    40 ALEAEGTH-GLGERVMA-------TLYLKSCRANSVVPVSCLLRQEGASELNLRHRGLGPQGVRA 96

  Fly   241 I------------------------AEHLA---RTNSKFRRLRIACNKIGPDGAFFLLRGMSMGG 278
            :                        ||.||   |.||....:.::.|:||..|...:...:::..
Mouse    97 LASVLTSNPYIKRLDLRDNGLCGAGAEALADVLRKNSIISDVDLSENQIGAAGLQAICTALALNP 161

  Fly   279 NLELLDLSYCSIGTHGGEWVAKYLASC----RRLQVLHLNYNDMGPTAVNLILLAMKKQCKLEKL 339
            .:|.:.|.    |....|..|::||:.    |.|:.|.|:||.:...|..::..|:.:...|.:|
Mouse   162 TVEKMQLQ----GNRLEEQAAQHLAALLLHHRGLKSLDLSYNQLNDLAGEILGPAVAENTGLTEL 222

  Fly   340 TLYGNHFDSRTAMIVRRLLDAEVVLHSELDISY 372
            .|..||.....|....|.|:|.:.| ..||||:
Mouse   223 NLSWNHLRGLGATAFARGLEANIFL-KVLDISH 254

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8197NP_001286225.1 leucine-rich repeat 134..161 CDD:275381
LRR_RI 137..374 CDD:238064 59/228 (26%)
leucine-rich repeat 162..189 CDD:275381 4/10 (40%)
leucine-rich repeat 202..220 CDD:275380 7/19 (37%)
leucine-rich repeat 223..251 CDD:275380 11/54 (20%)
leucine-rich repeat 252..279 CDD:275380 4/26 (15%)
leucine-rich repeat 280..307 CDD:275380 7/30 (23%)
leucine-rich repeat 308..335 CDD:275380 7/26 (27%)
leucine-rich repeat 336..357 CDD:275380 6/20 (30%)
Lrrc74bNP_083329.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..38
LRR_RI 56..353 CDD:238064 53/204 (26%)
leucine-rich repeat 81..106 CDD:275380 5/24 (21%)
LRR 1 106..126 2/19 (11%)
leucine-rich repeat 107..128 CDD:275380 4/20 (20%)
LRR 2 134..154 4/19 (21%)
leucine-rich repeat 159..190 CDD:275380 7/34 (21%)
LRR 3 162..182 5/23 (22%)
LRR_8 189..257 CDD:290566 22/67 (33%)
LRR 4 190..211 6/20 (30%)
leucine-rich repeat 191..218 CDD:275380 7/26 (27%)
LRR 5 218..239 6/20 (30%)
leucine-rich repeat 219..243 CDD:275380 8/23 (35%)
LRR 6 246..259 5/10 (50%)
leucine-rich repeat 247..270 CDD:275380 5/9 (56%)
LRR 7 274..294
leucine-rich repeat 275..292 CDD:275380
LRR 8 302..323
leucine-rich repeat 303..332 CDD:275380
LRR 9 332..354
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 371..391
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4308
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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