DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8197 and lrrc71

DIOPT Version :9

Sequence 1:	NP_001286225.1	Gene:	CG8197 / 35912	FlyBaseID:	FBgn0033369	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_001038339.1	Gene:	lrrc71 / 558774	ZFINID:	ZDB-GENE-060503-892	Length:	481	Species:	Danio rerio

Alignment Length:	354	Identity:	76/354 - (21%)
Similarity:	127/354 - (35%)	Gaps:	102/354 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 EYDKRPYRQFQFKRLTFEERIGRRYHC-IRDLRIIVNYLLRRPQLSVQISSLVVSNWDAGLLKDF 100
            :|....:.|.:|..|           | :..::.|.:..::||    :|....::.|..|
Zfish    29 DYQCSGHLQLEFPEL-----------CKLMGVKEIPSVKVKRP----RILESRMTKWSPG----- 73

  Fly   101 VRSLLPVWYIELRLMRFPREFFVMLRLNAAKMNVSQLSLEGTPLTDEDVRILREFLLVSKTLRRL 165
             |.|    .|||.              |....||.::.:.|..:.:..:::|.:.|.....|..|
Zfish    74 -RCL----QIELE--------------NEEHNNVKEVKISGWTVDELMLQVLSKILPSLSNLLCL 119

  Fly   166 NVSSCSLTQFNFALIADGVYKSPGVRRL----------SANRLLG-----MSLSLDTEKISSVLS 215
            .:....||...|..:.:.|.....:|::          |.:.|||     ..|||...:|....:
Zfish   120 RMWRIGLTDGTFTSMKNTVSLCSNLRKVVLEGNPLPEQSYHLLLGEDSMLTELSLRNNRIGEEGA 184

  Fly   216 SLLMQNTLWALSLEHCELTAQDMIPIAEHLARTNSKFRRLRIACNKIGPDGAFFLLRGMSMGGNL 280
            .|:..    |||..|                ..|...|.|.:|.|:||..||..:.:|:.:..:|
Zfish   185 RLIGS----ALSNPH----------------SANKNLRSLNLAYNRIGDAGALHIAQGLRLNRSL 229

  Fly   281 ELLDLSYCSIGTHGGEWVAKYLASCRRLQVLHLNYNDMGPTAVNLILLAMKKQCKLEKLTLYGNH 345
            ..|.|||..||.:|...:|:.|                ||.|     |..::..:..||.:.|:.
Zfish   230 LSLSLSYNHIGDNGAARLAEVL----------------GPFA-----LTHEEIVERRKLLIKGDQ 273

  Fly   346 FDSRTAMIVRRLLDA-----EVVLHSELD 369
            .:...:.:| .|.|:     .|..:|.||
Zfish   274 SNMVQSSLV-SLADSHEPALSVPSNSSLD 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8197	NP_001286225.1	leucine-rich repeat	134..161	CDD:275381	4/26 (15%)
		LRR_RI	137..374	CDD:238064	57/253 (23%)
		leucine-rich repeat	162..189	CDD:275381	6/26 (23%)
		leucine-rich repeat	202..220	CDD:275380	5/17 (29%)
		leucine-rich repeat	223..251	CDD:275380	5/27 (19%)
		leucine-rich repeat	252..279	CDD:275380	9/26 (35%)
		leucine-rich repeat	280..307	CDD:275380	10/26 (38%)
		leucine-rich repeat	308..335	CDD:275380	4/26 (15%)
		leucine-rich repeat	336..357	CDD:275380	4/20 (20%)
lrrc71	NP_001038339.1	LRR_RI	71..>251	CDD:238064	51/223 (23%)
		leucine-rich repeat	116..136	CDD:275380	5/19 (26%)
		leucine-rich repeat	144..168	CDD:275380	5/23 (22%)
		leucine-rich repeat	169..200	CDD:275380	10/50 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900