DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8197 and Nod1

DIOPT Version :9

Sequence 1:NP_001286225.1 Gene:CG8197 / 35912 FlyBaseID:FBgn0033369 Length:387 Species:Drosophila melanogaster
Sequence 2:NP_001102706.1 Gene:Nod1 / 500133 RGDID:1562269 Length:953 Species:Rattus norvegicus


Alignment Length:317 Identity:62/317 - (19%)
Similarity:116/317 - (36%) Gaps:80/317 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    63 CIRD---LRIIVNYLLRRPQLSVQISSLVVSNWDAGLLKDF-VRSLLPVWYIELRLMRFPREFFV 123
            |..|   |..::::..|  ||::.:        |...|.|: ||.|.|.:               
  Rat   688 CSADCSALSFVLHHFHR--QLALDL--------DNNNLNDYGVRELQPCF--------------- 727

  Fly   124 MLRLNAAKMNVSQLSLEGTPLTDEDVRILREFLLVSKTLRRLNVSSCSLTQFNFALIADGVYKSP 188
             .||...:::|:|       :||..|::|.|.|...|.:..|.:.:..:|......:|..:.:..
  Rat   728 -SRLTVIRLSVNQ-------ITDMGVKVLCEELTKYKIVTFLGLYNNQITDIGARYVAQILDECR 784

  Fly   189 GVR--RLSANRLLGMSLSLDTEKISSVLSSLLMQNTLWALSLEHCELTAQDMIPIAEHLARTNSK 251
            |:.  :|..||:.........:.:.:  |:.:::..:|.                          
  Rat   785 GLTHLKLGKNRITSEGGRCVAQAVKN--STSIVEVGMWG-------------------------- 821

  Fly   252 FRRLRIACNKIGPDGAFFLLRGMSMGGNLELLDLSYCSIGTHGGEWVAKYLASCRRLQVLHLNYN 316
                    |:||.:||......:....:|..|.|::..|...||:.:|:.|.....|.::.|..|
  Rat   822 --------NQIGDEGAKAFAEALRDHPSLTTLSLAFNGISPEGGKSLAQALKQNTTLTIIWLTKN 878

  Fly   317 DMGPTAVNLILLAMKKQCKLEKLTLYGNHFDSR-TAMIVRRLLD----AEVVLHSEL 368
            ::...|.......::....|:.|.|..||..:. ||.:.|.|..    .|:.|:..|
  Rat   879 ELNDEAAECFAEMLRVNQTLKHLWLIQNHITAEGTAQLARALQKNTTITEICLNGNL 935

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8197NP_001286225.1 leucine-rich repeat 134..161 CDD:275381 8/26 (31%)
LRR_RI 137..374 CDD:238064 45/239 (19%)
leucine-rich repeat 162..189 CDD:275381 3/26 (12%)
leucine-rich repeat 202..220 CDD:275380 1/17 (6%)
leucine-rich repeat 223..251 CDD:275380 1/27 (4%)
leucine-rich repeat 252..279 CDD:275380 5/26 (19%)
leucine-rich repeat 280..307 CDD:275380 8/26 (31%)
leucine-rich repeat 308..335 CDD:275380 4/26 (15%)
leucine-rich repeat 336..357 CDD:275380 8/21 (38%)
Nod1NP_001102706.1 DD 21..104 CDD:301326
NACHT 197..367 CDD:283404
LRR_RI <728..941 CDD:238064 49/251 (20%)
leucine-rich repeat 730..757 CDD:275380 9/33 (27%)
leucine-rich repeat 758..785 CDD:275380 3/26 (12%)
leucine-rich repeat 786..813 CDD:275380 4/28 (14%)
leucine-rich repeat 814..841 CDD:275380 6/60 (10%)
leucine-rich repeat 842..869 CDD:275380 8/26 (31%)
leucine-rich repeat 870..897 CDD:275380 4/26 (15%)
leucine-rich repeat 898..925 CDD:275380 9/26 (35%)
leucine-rich repeat 926..946 CDD:275380 3/10 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4308
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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