DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG8197 and Nlrp14

DIOPT Version :9

Sequence 1:NP_001286225.1 Gene:CG8197 / 35912 FlyBaseID:FBgn0033369 Length:387 Species:Drosophila melanogaster
Sequence 2:XP_038957056.1 Gene:Nlrp14 / 499234 RGDID:1598218 Length:1007 Species:Rattus norvegicus


Alignment Length:246 Identity:62/246 - (25%)
Similarity:108/246 - (43%) Gaps:42/246 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   124 MLRLNAAKMNVSQ----------------LSLEGTPLTDEDVRILREFL-LVSKTLRRLNVSSCS 171
            :|||.:..:||:.                |:|....|:::.|:.|.|.| ..:..|.||.::||.
  Rat   677 VLRLESCDLNVTHCQNLSKALQSNRSLVFLNLSTNSLSNDGVKSLCEVLENPNCPLERLALASCG 741

  Fly   172 LTQFNFALIADGVYKSPGVRRLSANRLLGMSLS---LDTEKISSVLSSLLM--QNTLWALSLEHC 231
            ||:....:::..:.|:        .||..:.|:   |:.|.| .:||..|.  :.||.:|.|..|
  Rat   742 LTKVGCEVLSSALTKT--------KRLTHLCLAHNVLEDEGI-ELLSYTLRHPRCTLQSLVLRCC 797

  Fly   232 ELTAQDMIPI-AEHLA---RTNSKFRRLRIACNKIGPDGAFFLLRGMSMGG-NLELLDLSYCSIG 291
            ..|     || :|||:   :.|.....|.:..||:...|...|.:.:.... ||:.|:|..|.:.
  Rat   798 YFT-----PIGSEHLSTALQNNKSLIHLDLGFNKLADSGVKLLCQTLQQPNCNLQELELMGCVLT 857

  Fly   292 THGGEWVAKYLASCRRLQVLHLNYNDMGPTAVNLILLAMKK-QCKLEKLTL 341
            :.....:|..|.:...|..|.|..|.:....:|::..|::. .|::.:|.|
  Rat   858 SEACGDLASVLVNNSNLWNLDLGNNILDDAGLNILCEALRNPNCQIRRLGL 908

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8197NP_001286225.1 leucine-rich repeat 134..161 CDD:275381 8/43 (19%)
LRR_RI 137..374 CDD:238064 57/217 (26%)
leucine-rich repeat 162..189 CDD:275381 8/26 (31%)
leucine-rich repeat 202..220 CDD:275380 7/22 (32%)
leucine-rich repeat 223..251 CDD:275380 11/31 (35%)
leucine-rich repeat 252..279 CDD:275380 5/27 (19%)
leucine-rich repeat 280..307 CDD:275380 6/26 (23%)
leucine-rich repeat 308..335 CDD:275380 6/27 (22%)
leucine-rich repeat 336..357 CDD:275380 2/6 (33%)
Nlrp14XP_038957056.1 NACHT 95..262 CDD:399032
NOD2_WH 339..394 CDD:407651
NLRC4_HD2 396..513 CDD:407648
LRR_RI <580..740 CDD:423007 15/62 (24%)
leucine-rich repeat 646..674 CDD:275381
LRR_RI 675..963 CDD:423007 62/246 (25%)
leucine-rich repeat 675..702 CDD:275381 5/24 (21%)
leucine-rich repeat 703..731 CDD:275381 7/27 (26%)
leucine-rich repeat 732..759 CDD:275381 8/34 (24%)
leucine-rich repeat 760..787 CDD:275381 8/27 (30%)
leucine-rich repeat 789..816 CDD:275381 11/31 (35%)
leucine-rich repeat 817..845 CDD:275381 5/27 (19%)
leucine-rich repeat 874..898 CDD:275380 6/23 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000189
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

Return to query results.
Submit another query.