DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8197 and CG7886

DIOPT Version :9

Sequence 1:	NP_001286225.1	Gene:	CG8197 / 35912	FlyBaseID:	FBgn0033369	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_650378.1	Gene:	CG7886 / 41775	FlyBaseID:	FBgn0038248	Length:	818	Species:	Drosophila melanogaster

Alignment Length:	268	Identity:	58/268 - (21%)
Similarity:	91/268 - (33%)	Gaps:	98/268 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 LVVSNWDAGLLKDFVRSLLPVWYIELRLMR-------------------------FPREFF---- 122
            |.||:|.  ||.:.:...|.:..:.:||.|                         :.|..|
  Fly    78 LAVSDWQ--LLTEALHYDLVLQQLVVRLRRTYPQTNIDPIDTEKRARLFRQRPVIYTRFIFNSLV 140

  Fly   123 -VMLRLNAAKMNVSQLSLEGTPLTDEDVRILREFL----------------------LVSKTLRR 164
             .:....::..|:|.|.|||.||.|..:..:.:.|                      :|..|.:.
  Fly   141 QAIANCVSSNKNLSVLKLEGLPLQDGYIETIAKALADNECLESVSFRKSNIGDKGCEVVCNTAKY 205

  Fly   165 LN------VSSCSLTQFNFALIAD------------GVYKSPGVRRLSANRLLGMS--LSLDTEK 209
            ||      :|.|.||......:||            |..||...|.:..|.:.|:.  |..|..:
  Fly   206 LNRIEVFDLSECGLTSKGAEHVADMLKMQKITRFTEGWEKSLRYRSVDVNTIGGLRTVLLADNPE 270

  Fly   210 ISSV----LSSLLMQNTLW--ALSLEHCELT--AQDMI--------PIAEHLARTN---SKFRRL 255
            |..|    ::.:|.::. |  .:.:|.|.||  ..::|        .|.|...|.|   |||.:.
  Fly   271 IGDVGIRWITEVLKEDA-WIKKIDMEGCGLTDIGANLILDCLELNTAITEFNVRNNEGISKFLQR 334

  Fly   256 ----RIAC 259
                |:.|
  Fly   335 SIHDRLGC 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8197	NP_001286225.1	leucine-rich repeat	134..161	CDD:275381	10/48 (21%)
		LRR_RI	137..374	CDD:238064	44/188 (23%)
		leucine-rich repeat	162..189	CDD:275381	11/44 (25%)
		leucine-rich repeat	202..220	CDD:275380	5/23 (22%)
		leucine-rich repeat	223..251	CDD:275380	10/42 (24%)
		leucine-rich repeat	252..279	CDD:275380	3/12 (25%)
		leucine-rich repeat	280..307	CDD:275380
		leucine-rich repeat	308..335	CDD:275380
		leucine-rich repeat	336..357	CDD:275380
CG7886	NP_650378.1	LRR_RI	<142..320	CDD:238064	38/178 (21%)
		leucine-rich repeat	153..180	CDD:275381	9/26 (35%)
		leucine-rich repeat	181..208	CDD:275381	3/26 (12%)
		leucine-rich repeat	209..246	CDD:275381	7/36 (19%)
		leucine-rich repeat	260..285	CDD:275381	5/24 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4308
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900