| Sequence 1: | NP_001286225.1 | Gene: | CG8197 / 35912 | FlyBaseID: | FBgn0033369 | Length: | 387 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_789792.1 | Gene: | NLRP14 / 338323 | HGNCID: | 22939 | Length: | 1093 | Species: | Homo sapiens |
| Alignment Length: | 476 | Identity: | 108/476 - (22%) |
|---|---|---|---|
| Similarity: | 169/476 - (35%) | Gaps: | 150/476 - (31%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 21 EKSRLFTIL---------LLYCWQ------------REYDKRPYRQFQFKRLTFEERIGRRYHCI 64
Fly 65 RDLRI--IVNYLLRRPQLSVQISSLVVSNWDAGLLKDFVRSLL---PVWYIELR----------- 113
Fly 114 ---LMRFPREFFVMLRLNAAKMNV------------SQ----LSLEGTPLTDEDVRILREFLLVS 159
Fly 160 KT-LRRLNVSSCSLTQ-----FNFALI----------ADGVYKSPGVRRLS------ANRLLGMS 202
Fly 203 L------SLDTEKISSVL------------SSLLMQN--------------TLWALSLEHCELTA 235
Fly 236 QDMIPIAEHLARTNSKFRRLRIACNKIGPDGAFFLLRGMSMGG-NLELLDLSYCSIGTHGGEWVA 299
Fly 300 KYLASCRRLQVLHLNYNDMGPTAVNLILLAMKK-QCKLEKLTLYGNHFDSRTAMIVRRLLDAEVV 363
Fly 364 ------------LHSELDISY 372 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG8197 | NP_001286225.1 | leucine-rich repeat | 134..161 | CDD:275381 | 11/42 (26%) |
| LRR_RI | 137..374 | CDD:238064 | 76/304 (25%) | ||
| leucine-rich repeat | 162..189 | CDD:275381 | 13/41 (32%) | ||
| leucine-rich repeat | 202..220 | CDD:275380 | 8/35 (23%) | ||
| leucine-rich repeat | 223..251 | CDD:275380 | 8/27 (30%) | ||
| leucine-rich repeat | 252..279 | CDD:275380 | 6/27 (22%) | ||
| leucine-rich repeat | 280..307 | CDD:275380 | 5/26 (19%) | ||
| leucine-rich repeat | 308..335 | CDD:275380 | 5/27 (19%) | ||
| leucine-rich repeat | 336..357 | CDD:275380 | 5/20 (25%) | ||
| NLRP14 | NP_789792.1 | Pyrin_NALPs | 15..97 | CDD:260032 | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 102..121 | ||||
| AAA | 175..308 | CDD:214640 | |||
| NACHT | 179..346 | CDD:283404 | |||
| LRR_RI | 531..884 | CDD:238064 | 59/264 (22%) | ||
| leucine-rich repeat | 675..730 | CDD:275380 | 16/75 (21%) | ||
| YjbI | 701..971 | CDD:224276 | 60/271 (22%) | ||
| LRR 1 | 730..750 | 1/19 (5%) | |||
| leucine-rich repeat | 731..759 | CDD:275380 | 2/27 (7%) | ||
| LRR_RI | 732..1050 | CDD:238064 | 73/318 (23%) | ||
| LRR 2 | 759..780 | 4/20 (20%) | |||
| leucine-rich repeat | 760..787 | CDD:275380 | 5/26 (19%) | ||
| LRR 3 | 787..807 | 5/19 (26%) | |||
| leucine-rich repeat | 788..812 | CDD:275380 | 8/23 (35%) | ||
| LRR 4 | 816..836 | 7/19 (37%) | |||
| leucine-rich repeat | 817..844 | CDD:275380 | 10/26 (38%) | ||
| LRR 5 | 844..864 | 5/19 (26%) | |||
| leucine-rich repeat | 845..873 | CDD:275380 | 6/27 (22%) | ||
| LRR 6 | 873..894 | 5/20 (25%) | |||
| leucine-rich repeat | 874..901 | CDD:275380 | 7/26 (27%) | ||
| LRR 7 | 901..921 | 3/19 (16%) | |||
| leucine-rich repeat | 902..930 | CDD:275380 | 3/27 (11%) | ||
| LRR 8 | 930..951 | 6/20 (30%) | |||
| leucine-rich repeat | 931..958 | CDD:275380 | 8/27 (30%) | ||
| LRR 9 | 958..978 | 5/19 (26%) | |||
| leucine-rich repeat | 959..980 | CDD:275380 | 6/20 (30%) | ||
| leucine-rich repeat | 981..1008 | CDD:275380 | 5/26 (19%) | ||
| LRR 10 | 987..1008 | 5/20 (25%) | |||
| LRR 11 | 1015..1035 | 5/19 (26%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000189 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.910 | |||||