Protein Alignment CG8197 and Nlrp9

DIOPT Version :10

• Sequence 1: NP_610445.1
• Gene: CG8197 / 35912
• FlyBaseID: FBgn0033369
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_001162620.1
• Gene: Nlrp9 / 292577
• RGDID: 1308981
• Length: 1003
• Species: Rattus norvegicus
• Alignment Length: 411
• Identity: 97/411 - (23%)
• Similarity: 151/411 - (36%)
• Gaps: 101/411 - (24%)

  Fly     1 MCDVLLPCEYNPKECPSPAAEKSRLFTILLLYCWQREYDKRPYRQFQFKRL--TFEERI--GRRY 61
            :|:||         .|||                     |.|...|:.:.|  :|....  |..:
  Rat   651 LCNVL---------SPSP---------------------KIPLMAFKLESLLCSFMTNFGDGSLF 685

  Fly    62 HCIRDLRIIVNYLLRRPQL------SVQISSLVVSNWDAGLLKDFVRSLLPVWYIELRLMRFPRE 120
            |.          ||:.|.|      ...:|:..:.|    |.....||...|..:.|.......|
  Rat   686 HT----------LLQLPHLKYLNLYGTNLSNSRIEN----LCSALRRSTCKVEELLLGKCDISSE 736

  Fly   121 FFVMLRLNAAKMNVSQLSLEGTPLTDEDVRILREFLL-VSKTLRRLNVSSCSLTQFNFALIADG- 183
            ...::..:.....|..|||...||.::.|..|.|.|. .|..|..|.:|.|.||     .||.|
  Rat   737 ACGIIATSLMNSKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLETLMLSYCCLT-----FIACGH 796

  Fly   184 VYKSPGVRRLSANRLLGMSLSLDTEKISSVLSSLLMQ---------NTLWALSLEHCELTAQDMI 239
            :|::     |.:|:.|.: |.|.:..:.....:||.:         ..||   |..|.||::...
  Rat   797 LYEA-----LVSNKHLSL-LDLGSNFLEDTGVNLLCEALKDPNCILKELW---LSGCFLTSECCE 852

  Fly   240 PIAEHLARTNSKFRRLRIACNKIGPDGAFFLLRGMSMGG-NLELLDLSYCSIGTHGGEWVAKYLA 303
            .|:..|. .|:..:.|::..|.|...|...|...:|... .||.|.|..|...:...|.:|..|.
  Rat   853 EISAVLT-CNNNLKTLKLGNNDIEDTGVKHLCEALSHPNCKLECLGLDLCKFTSDCCEDLASALT 916

  Fly   304 SCRRLQVLHLNYNDMGPTAVNLILLAMK-KQCKLEKLTLYGNHF--DSRTAMIVRRLLDAEVVLH 365
            :|:.|..|:|::..:..:.|..:..|:. |:|.|:.|.|..:.|  :|:|      ||.|....:
  Rat   917 TCKTLNSLNLDWKTLEHSGVVALCEALNHKKCNLKMLGLDKSAFSVESQT------LLQAVEKKN 975

  Fly   366 SELDISYTYDEALQDYRVVPW 386
            :.|.|.:           .||
  Rat   976 NNLSILH-----------YPW 985

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8197	NP_610445.1	RNA1	<133..345	CDD:444072	62/224 (28%)
		leucine-rich repeat	202..220	CDD:275380	4/17 (24%)
		leucine-rich repeat	223..251	CDD:275380	9/27 (33%)
		leucine-rich repeat	252..279	CDD:275380	6/27 (22%)
		leucine-rich repeat	280..307	CDD:275380	9/26 (35%)
		leucine-rich repeat	308..335	CDD:275380	6/27 (22%)
		leucine-rich repeat	336..357	CDD:275380	6/22 (27%)
Nlrp9	NP_001162620.1	Pyrin_NALPs	9..90	CDD:260032
		P-loop containing Nucleoside Triphosphate Hydrolases	144..308	CDD:476819
		NOD2_WH	385..>430	CDD:465501
		NLRC4_HD2	440..555	CDD:465499
		leucine-rich repeat	633..667	CDD:275381	8/45 (18%)
		leucine-rich repeat	668..687	CDD:275381	3/18 (17%)
		PPP1R42	691..956	CDD:455733	71/283 (25%)
		leucine-rich repeat	694..722	CDD:275380	6/31 (19%)
		leucine-rich repeat	723..749	CDD:275380	3/25 (12%)
		leucine-rich repeat	750..778	CDD:275380	11/27 (41%)
		leucine-rich repeat	779..806	CDD:275380	12/36 (33%)
		leucine-rich repeat	807..834	CDD:275380	5/27 (19%)
		leucine-rich repeat	836..863	CDD:275380	9/30 (30%)
		leucine-rich repeat	893..920	CDD:275381	9/26 (35%)
		leucine-rich repeat	921..949	CDD:275381	6/27 (22%)