DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8197 and Lrrc45

DIOPT Version :9

Sequence 1:NP_001286225.1 Gene:CG8197 / 35912 FlyBaseID:FBgn0033369 Length:387 Species:Drosophila melanogaster
Sequence 2:NP_705773.2 Gene:Lrrc45 / 217366 MGIID:2387183 Length:670 Species:Mus musculus


Alignment Length:252 Identity:70/252 - (27%)
Similarity:109/252 - (43%) Gaps:22/252 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly   137 LSLEGTPLTDEDVRILREFLLVSKTLRRLNVSSCSLTQFNFALIADGVYKSPGVRRLSANRLLGM 201
            |.|....||.|..|.|.:.|.....|:.|.:|.|.|::....|:..|:..:..|:.|.   |.|.
Mouse    35 LDLTTQSLTVETCRALGKLLHKETLLKELVLSDCMLSEEGSTLLFQGLCANTSVQHLD---LKGN 96

  Fly   202 SLSLDTEKISSVLSSLLMQN-TLWALSLEHCEL-TAQDMIPIAEHLARTNSKFRRLRIACNKIGP 264
            :|....   :..|..||.|| ::.:|:||...| |.:|...........||..|:|.:..|:|..
Mouse    97 NLRATG---AEALGKLLRQNKSIQSLTLEWNNLGTWEDAFATFCGGLAANSALRQLDLRNNQISH 158

  Fly   265 DGAFFLLRGMSMGGNLELLDLSYCSIGTHGGEWVAKYLASCRRLQVLHLNYNDMGPTAVNLILLA 329
            .||..|...:.....|:.|||.:.:||..||..:...|.|.|.|..|.|..|::....:..:..|
Mouse   159 KGAEELALALKGNTTLQQLDLRWNNIGLLGGRALVNCLPSNRTLWKLDLAGNNIPGDILRAVEQA 223

  Fly   330 MKKQCKLEKLTLYGNHFDSRTAMIVRRLLDAEVV-LHSE-----LDISYTYDEALQD 380
            |..  ..::||.:..: .:||     ::|..||. |..|     ||:..|.|:..::
Mouse   224 MDH--NQDRLTAFREN-QART-----KILSKEVQHLQEEKSKQFLDLMETIDKQREE 272

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8197NP_001286225.1 leucine-rich repeat 134..161 CDD:275381 8/23 (35%)
LRR_RI 137..374 CDD:238064 68/244 (28%)
leucine-rich repeat 162..189 CDD:275381 7/26 (27%)
leucine-rich repeat 202..220 CDD:275380 4/17 (24%)
leucine-rich repeat 223..251 CDD:275380 7/28 (25%)
leucine-rich repeat 252..279 CDD:275380 7/26 (27%)
leucine-rich repeat 280..307 CDD:275380 10/26 (38%)
leucine-rich repeat 308..335 CDD:275380 6/26 (23%)
leucine-rich repeat 336..357 CDD:275380 4/20 (20%)
Lrrc45NP_705773.2 leucine-rich repeat 30..55 CDD:275380 7/19 (37%)
LRR_RI <35..229 CDD:393385 57/201 (28%)
LRR 1 59..79 6/19 (32%)
leucine-rich repeat 60..87 CDD:275380 7/26 (27%)
LRR 2 87..108 6/26 (23%)
leucine-rich repeat 88..115 CDD:275380 10/32 (31%)
LRR 3 115..136 6/20 (30%)
leucine-rich repeat 116..145 CDD:275380 7/28 (25%)
LRR 4 145..166 7/20 (35%)
leucine-rich repeat 146..173 CDD:275380 7/26 (27%)
LRR 5 173..194 8/20 (40%)
leucine-rich repeat 174..201 CDD:275380 10/26 (38%)
LRR 6 201..223 4/21 (19%)
SMC_prok_B <267..608 CDD:274008 1/6 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 332..352
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4308
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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