DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8197 and LRRC34

DIOPT Version :9

Sequence 1:NP_001286225.1 Gene:CG8197 / 35912 FlyBaseID:FBgn0033369 Length:387 Species:Drosophila melanogaster
Sequence 2:NP_001166250.1 Gene:LRRC34 / 151827 HGNCID:28408 Length:464 Species:Homo sapiens


Alignment Length:251 Identity:51/251 - (20%)
Similarity:104/251 - (41%) Gaps:36/251 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   137 LSLEGTPLTDEDVRILREFLLVSKTLRRLNVSSCSLTQFNFALIADGVYKSPGVRRLSANRLLGM 201
            |.:.|..:.::........|.::.:|.:|::..|.|...:....|..:.::..::.::.||.:  
Human   184 LRMTGNKIENKGGMFFAAMLQINSSLEKLDLGDCDLGMQSVIAFATVLTQNQAIKAINLNRPI-- 246

  Fly   202 SLSLDTEKISSVLSSLLMQNTLWALSLEHCELTAQDMIPIAEHLAR----------------TNS 250
             |..:.|:.:..:..:|.:|        ||        .:|.|:.:                .||
Human   247 -LYSEQEESTVHVGRMLKEN--------HC--------LVALHMCKHDIKNSGIQQLCDALYLNS 294

  Fly   251 KFRRLRIACNKIGPDGAFFLLRGMSMGGNLELLDLSYCSIGTHGGEWVAKYLASCRR-LQVLHLN 314
            ..|.|.::||||..||..:|...:.....||::|||:..|...|..::::.|.|..| |:.|.:.
Human   295 SLRYLDVSCNKITHDGMVYLADVLKSNTTLEVIDLSFNRIENAGANYLSETLTSHNRSLKALSVV 359

  Fly   315 YNDMGPTAVNLILLAMKKQCKLEKLTLYGNHFDSRTAMIVRRLLDAEVVLHSELDI 370
            .|::....:..:..:||.......:.::||.||..|.:....|:....:.....|:
Human   360 SNNIEGEGLVALSQSMKTNLTFSHIYIWGNKFDEATCIAYSDLIQMGCLKPDNTDV 415

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8197NP_001286225.1 leucine-rich repeat 134..161 CDD:275381 3/23 (13%)
LRR_RI 137..374 CDD:238064 51/251 (20%)
leucine-rich repeat 162..189 CDD:275381 5/26 (19%)
leucine-rich repeat 202..220 CDD:275380 3/17 (18%)
leucine-rich repeat 223..251 CDD:275380 5/43 (12%)
leucine-rich repeat 252..279 CDD:275380 9/26 (35%)
leucine-rich repeat 280..307 CDD:275380 9/26 (35%)
leucine-rich repeat 308..335 CDD:275380 5/26 (19%)
leucine-rich repeat 336..357 CDD:275380 5/20 (25%)
LRRC34NP_001166250.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..48
LRR_RI <147..396 CDD:330982 48/230 (21%)
leucine-rich repeat 153..180 CDD:275380
leucine-rich repeat 181..208 CDD:275380 3/23 (13%)
leucine-rich repeat 209..244 CDD:275380 5/34 (15%)
leucine-rich repeat 268..295 CDD:275380 3/26 (12%)
LRR 1 295..315 8/19 (42%)
leucine-rich repeat 296..323 CDD:275380 9/26 (35%)
LRR 2 323..345 7/21 (33%)
leucine-rich repeat 324..352 CDD:275380 9/27 (33%)
leucine-rich repeat 353..374 CDD:275380 3/20 (15%)
leucine-rich repeat 375..402 CDD:275380 7/26 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4308
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 61 1.000 Inparanoid score I5393
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53944
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - oto89068
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
65.870

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