DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8197 and tcte1

DIOPT Version :9

Sequence 1:	NP_001286225.1	Gene:	CG8197 / 35912	FlyBaseID:	FBgn0033369	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	XP_002942200.2	Gene:	tcte1 / 100487694	XenbaseID:	XB-GENE-996398	Length:	460	Species:	Xenopus tropicalis

Alignment Length:	219	Identity:	60/219 - (27%)
Similarity:	94/219 - (42%)	Gaps:	43/219 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 LRLMRFPREFFVMLRLNAAKMN----------------VSQLSLEGTPLTDEDVRILREFLLVSK 160
            ||:.|..:.|    ||:.:|::                :..|.|....::|...|.:.: ||...
Frog   246 LRVFRNLKVF----RLHKSKVDDDKACVLVRSLLNHPALVHLDLSHNQVSDRGARAIAK-LLKES 305

  Fly   161 TLRRLNVSSCSLTQFNFALIADGVYKSPGVRRLSANR--LLGMSLSLD---TEKISSVLSSLLMQ 220
            .||.|::|:.::          |.:.:..:.....|.  |..:||.|:   .|...::.::||..
Frog   306 ALRVLDLSNNNV----------GAHGAQALAHALTNNWTLRNLSLRLNHVGNEGGQALCNALLPN 360

  Fly   221 NTLWALSLEHCELTAQDMIPIAEHLART---NSKFRRLRIACNKIGPDGAFFLLRGMSMGGNLEL 282
            .||..|.|...||:.    |.|..|::.   |...|||.:|||:|||||...||.|||....|..
Frog   361 QTLQELHLGSNELSE----PTASALSQALTHNGSLRRLSLACNRIGPDGGKQLLEGMSDNETLLE 421

  Fly   283 LDLSYCSIGTHGGEWVAKYLASCR 306
            |||....||.....::.:.|.:.|
Frog   422 LDLRLTEIGQESEFFINQVLKNNR 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8197	NP_001286225.1	leucine-rich repeat	134..161	CDD:275381	6/26 (23%)
		LRR_RI	137..374	CDD:238064	53/178 (30%)
		leucine-rich repeat	162..189	CDD:275381	5/26 (19%)
		leucine-rich repeat	202..220	CDD:275380	6/20 (30%)
		leucine-rich repeat	223..251	CDD:275380	9/30 (30%)
		leucine-rich repeat	252..279	CDD:275380	16/26 (62%)
		leucine-rich repeat	280..307	CDD:275380	8/27 (30%)
		leucine-rich repeat	308..335	CDD:275380
		leucine-rich repeat	336..357	CDD:275380
tcte1	XP_002942200.2	LRR_RI	152..448	CDD:238064	60/219 (27%)
		leucine-rich repeat	280..306	CDD:275380	6/26 (23%)
		leucine-rich repeat	307..331	CDD:275380	5/33 (15%)
		leucine-rich repeat	335..360	CDD:275380	7/24 (29%)
		leucine-rich repeat	363..390	CDD:275380	9/30 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910