DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8197 and tcte1

DIOPT Version :9

Sequence 1:	NP_001286225.1	Gene:	CG8197 / 35912	FlyBaseID:	FBgn0033369	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	XP_009293283.1	Gene:	tcte1 / 100331698	ZFINID:	ZDB-GENE-120406-12	Length:	450	Species:	Danio rerio

Alignment Length:	432	Identity:	86/432 - (19%)
Similarity:	154/432 - (35%)	Gaps:	113/432 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LFTILLLYCWQ---REYDKRPY---RQFQFKRLTFEERIGRRYHCIRDLRIIVNYLLRR--PQLS 81
            |..:|...|.|   :.::::|.   .|..||                      .|:|:|  ..|.
Zfish    38 LVPLLTTLCLQHIIKHFEEKPILHELQPSFK----------------------TYVLQRLPASLP 80

  Fly    82 VQISSLVVSN-----------WDAGLLKDFVRSLLPVWYIELRLMRFPREFFVMLRLNAAKMNVS 135
            :.|::.::|:           |....:..:..|    |    :.|.|.|....::.|.......:
Zfish    81 LTITANLISDESYWKRCCEARWGLADISTYDNS----W----KQMFFERHLQSIIELFIPDTTDT 137

  Fly   136 QLSLEGTPLTDEDVRILREFLLV--------------SKTLRRLNVSSCSLTQFNFALIADGVYK 186
            :..|:..||....|:.||...|:              |::...:.....|:..|:|.::.|   |
Zfish   138 KTVLDVLPLCQNYVKQLRVSQLLPPIKEPSRFDEDDGSESASDMGSDGPSMDHFDFRMLLD---K 199

  Fly   187 SPGVRRLSANRLL---GMSL---------------------------------SLDTEKISSVLS 215
            .|.::.||....:   ||:.                                 .:|.||...:::
Zfish   200 LPNLKELSVVYCVKGCGMNFEWNLFEFTFRDCESLAKALNSCKTLQVFRIHRSKVDDEKCCVIVN 264

  Fly   216 SLLMQNTLWALSLEHCELTAQDMIPIAEHLARTNSKFRRLRIACNKIGPDGAFFLLRGMSMGGNL 280
            .||...:|..|...|..::.:....||:.|.|  |:.:.|.:..|:|...||..|...::....|
Zfish   265 HLLDHPSLQELDFSHNHISDRGARAIAKLLNR--SQLKTLIVCNNQIRGAGAQALAHALAKNNTL 327

  Fly   281 ELLDLSYCSIGTHGGEWVAKYLASCRRLQVLHLNYNDMGPTAVNLILLAMKKQCKLEKLTLYGNH 345
            ..|:|....|...||:.:|:.|...:.|..|||..|:|...|...:..|:.:.|.|:.|.|..|.
Zfish   328 TSLNLRLNRIADEGGQALAQALIKNKTLVNLHLGGNNMTEPAAVALSQALVENCALKSLNLCNNR 392

  Fly   346 FDSRTAMIVRRLLDAEVVLHS----ELDISYTYDEALQDYRV 383
            ..:....::.     |.:.|:    |.||..|..:...:|.:
Zfish   393 LGADGGKVLE-----EGMTHNCTLVECDIRLTDVDQDSEYSI 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8197	NP_001286225.1	leucine-rich repeat	134..161	CDD:275381	8/40 (20%)
		LRR_RI	137..374	CDD:238064	63/290 (22%)
		leucine-rich repeat	162..189	CDD:275381	5/26 (19%)
		leucine-rich repeat	202..220	CDD:275380	5/50 (10%)
		leucine-rich repeat	223..251	CDD:275380	7/27 (26%)
		leucine-rich repeat	252..279	CDD:275380	6/26 (23%)
		leucine-rich repeat	280..307	CDD:275380	8/26 (31%)
		leucine-rich repeat	308..335	CDD:275380	8/26 (31%)
		leucine-rich repeat	336..357	CDD:275380	4/20 (20%)
tcte1	XP_009293283.1	LRR_RI	142..441	CDD:238064	64/298 (21%)
		leucine-rich repeat	272..298	CDD:275380	7/27 (26%)
		leucine-rich repeat	299..322	CDD:275380	6/22 (27%)
		leucine-rich repeat	327..354	CDD:275380	8/26 (31%)
		leucine-rich repeat	355..382	CDD:275380	8/26 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900