DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8197 and cep78

DIOPT Version :9

Sequence 1:	NP_001286225.1	Gene:	CG8197 / 35912	FlyBaseID:	FBgn0033369	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	XP_031751460.1	Gene:	cep78 / 100037836	XenbaseID:	XB-GENE-5884411	Length:	763	Species:	Xenopus tropicalis

Alignment Length:	190	Identity:	46/190 - (24%)
Similarity:	82/190 - (43%)	Gaps:	18/190 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 NVSQLSLEGTPLTDEDVRILREFLLVSKTLRRLNVSSCSLTQFNFALIADGVYKSPGVRRLSANR 197
            ::.:|.|.|.||.:.|:|||.:.|..|.::..|:::.||.......:|...|..||.::.::
Frog   122 SLKELELHGLPLRERDLRILAKGLAASSSVESLSLAYCSCGDEGLEIICQSVKNSPTIKTVN--- 183

  Fly   198 LLGMSLS-LDTEKISSVL--SSLLMQNTLWALSLEHCELTAQDMIPIAEHLARTNSKFRRLRIAC 259
            ..|.:|: ...|.|:|::  .:....:..||.||.:..       |..:.:|    ..||:.:..
Frog   184 FTGCNLTWRGAEHIASIIKHQATRRHSEAWAESLRYRR-------PDLDCMA----GLRRVTLNS 237

  Fly   260 NK-IGPDGAFFLLRGMSMGGNLELLDLSYCSIGTHGGEWVAKYLASCRRLQVLHLNYNDM 318
            |. :|..||..|...:.....|:.|||..|.|...|.:.......:...|.:|.:..|.:
Frog   238 NTLVGDRGAIALAEVIGEDLWLKALDLRQCGISNEGAQAFLNAFQTNTTLIILDIRRNPL 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8197	NP_001286225.1	leucine-rich repeat	134..161	CDD:275381	11/26 (42%)
		LRR_RI	137..374	CDD:238064	46/186 (25%)
		leucine-rich repeat	162..189	CDD:275381	6/26 (23%)
		leucine-rich repeat	202..220	CDD:275380	4/20 (20%)
		leucine-rich repeat	223..251	CDD:275380	6/27 (22%)
		leucine-rich repeat	252..279	CDD:275380	7/27 (26%)
		leucine-rich repeat	280..307	CDD:275380	7/26 (27%)
		leucine-rich repeat	308..335	CDD:275380	3/11 (27%)
		leucine-rich repeat	336..357	CDD:275380
cep78	XP_031751460.1	LRR_RI	<110..275	CDD:423007	43/166 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910