Protein Alignment Ance-4 and Ance-5

DIOPT Version :9

• Sequence 1: NP_610442.2
• Gene: Ance-4 / 35909
• FlyBaseID: FBgn0033366
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_573392.2
• Gene: Ance-5 / 37980
• FlyBaseID: FBgn0035076
• Length: 628
• Species: Drosophila melanogaster
• Alignment Length: 673
• Identity: 184/673 - (27%)
• Similarity: 302/673 - (44%)
• Gaps: 125/673 - (18%)

  Fly     1 MGLLLLLVLIAGIGCATAAANIDLEAKTFVNQSSDRYYRFYN----------------------- 42
            :.|:|||.:..|||    .::.:|..|..::::.||....::
  Fly     8 VSLILLLSVTFGIG----QSSYELATKQILDRAKDRMRHVWSLNRRIFVQLTAKGKSPLGGQVLN 68

  Fly    43 ---EIAAETYSANNEEDFDALFSKLNNVKRIAEELVSISRQAATYDLDRIRSPQTKMALQELRTA 104
               |:.||||..     |..|...| :|..:||....:.|:       |::. ..|:.||.||.
  Fly    69 SKLEVEAETYRL-----FYDLAGNL-SVVSVAELNDPLLRR-------RVQR-MAKLQLQGLRP- 118

  Fly   105 GDLFVLGDDYFSSVQMNLAALQTLSTDKDIEPYLGGANM-PNEDDS---PLAYFPDIQKIVQSSK 165
                   .||          .|.....:.|..::.|..: |.||.|   .||.:|.|......:|
  Fly   119 -------KDY----------EQAKDLLRQIHNFVNGPLVCPYEDCSARGSLAMYPQIMNKNMHTK 166

  Fly   166 DADELKYYWEAWR--------DKNQLWASLNFYTIVQSYQRAAKILEVPVHKLWY-RYDSQEMLQ 221
            ..::|...|:|||        .||.....:....|..:|..     .|...:.|| .||::....
  Fly   167 LYEDLVINWKAWRRAINEKDVAKNTFIGYVRLLRIAATYNG-----HVTPSRTWYLNYDTENFQA 226

  Fly   222 QMEQAMTELRPAYQQLHAFVRQELHKKYGSDVVNLNGPIPDHLFQQVLEQAWASGSILEDYYP-- 284
            :||..:.|:.|.|::|||::|:|:...|.......:|.|...:..|:|.|.|         ||
  Fly   227 EMEAVVWEIMPLYRELHAYLRREVQAAYPKADTKSDGAISAPIMDQILSQDW---------YPHQ 282

  Fly   285 ---------RAQLPEFDEYVSH-LTAKTMVN-ESENFYTSLGFEPLSAEFHKNQLKEPNQDSPND 338
                     :.|||.....:.. |.....:| ::..|:.|||...:...|:....:..|.:....
  Fly   283 FFRTPHQGRQHQLPSVHRRLEEVLVTPVKINRKAAEFFESLGLMVMPNIFYDRFSRRMNDEEGGA 347

  Fly   339 DCRPSIFDLTPHVYLMYCEKVSFRKLMQYHSHMARVYYAQQKSHLPSYYFKAYNLE--------F 395
            :|:..::...|.|.|.||.|:.::|:||.|..||.:.|...|..||      :.|:        .
  Fly   348 ECKSQVYYFPPDVALRYCPKLDYKKMMQIHGTMAELQYHLYKMQLP------FGLDTEPCPGFGA 406

  Fly   396 AVGEAVVLSASSPAHLTGRR-LAKEVLSETALMSRLFRMAIHTILSIPLYYVHTKVMHDLLNDTV 459
            |:.|.|:|::.:|.||.... |..:.|:|...::|||||.:||::::|.|:::.|.:.|:::..:
  Fly   407 AIAETVILASGTPRHLHRLHILLNDSLTEEQSLNRLFRMGVHTLIAVPQYFINDKFLVDVMDGRI 471

  Fly   460 DMDTVNKHYWRLMEQHAGIEAPSDRSEGAIDFPYKFYVNID-QSFQTQKFISEVLGYQFYREFCK 523
            .:...|..||.|.::.||::.|..|.....|..:|||..:: ::..|:||::|:||:||||.||.
  Fly   472 GVKDYNCAYWGLQDKFAGVQPPLQRLNKDFDVDFKFYRGLNPETSNTKKFLAEILGFQFYRSFCL 536

  Fly   524 KS--YNRG----PLHNCDFYGSLAVGNDLKAMMSLGSTKPWKQVVGKILPNNTGLSSLALLEYYQ 582
            .|  |..|    ||||||||.|...|..::.||.||:|:.|:.|: :|......||...:|||:.
  Fly   537 ASGQYKPGDPNFPLHNCDFYDSKEAGKKIRDMMQLGATRHWRDVM-EIATGERKLSGRGILEYFA 600

  Fly   583 PVLDWLNKYNKDANSKIGWTASK 605
            |:..||.:.||..:.:.||.|.:
  Fly   601 PLFTWLKERNKQLDIEPGWDADE 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance-4	NP_610442.2	GluZincin	25..601	CDD:301352	173/643 (27%)
Ance-5	NP_573392.2	GluZincin	93..610	CDD:301352	159/563 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455767
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3690
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D16282at33392
OrthoFinder	1	1.000	-	-		FOG0000442
OrthoInspector	1	1.000	-	-		otm14376
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10514
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.850