Protein Alignment Ance-4 and Ance-2

DIOPT Version :10

• Sequence 1: NP_610442.2
• Gene: Ance-4 / 35909
• FlyBaseID: FBgn0033366
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_788042.1
• Gene: Ance-2 / 34806
• FlyBaseID: FBgn0032535
• Length: 611
• Species: Drosophila melanogaster
• Alignment Length: 653
• Identity: 169/653 - (25%)
• Similarity: 282/653 - (43%)
• Gaps: 93/653 - (14%)

  Fly     1 MGLLLLLVLIAGIGCATAAANIDLEAKTFVNQSSDRYYRFYNEIAAETYSANNEEDFDALFSKLN 65
            |.:..:|:|   :|...|.:..|...:.|:|:::.:....|::               |:.::|.
  Fly     1 MWIFAVLLL---VGLTQAGSQPDATLERFLNETNQQLAVIYDQ---------------AVLAQLL 47

  Fly    66 NVKRIAEELVSISRQAATYD--LDRIRSPQTKMALQELRTAGD---------LFVLGDDYFSSVQ 119
            |..|...:||::.....|.|  :..:|:..|:.|..:....||         :..||.:..|...
  Fly    48 NELRGPNDLVALLEIEVTDDKLVKYVRTLTTRKAKFKRLGLGDSRQRRLLDKIPQLGYEALSGRD 112

  Fly   120 MNLA-ALQTLSTDKDIEPYLGGANMPNEDDSPLAYFPDIQKIVQSSKDADELKYYWEAWRDKNQL 183
            :.|. ||.:..:|......|.....|.  :..|...|::|.|||.|:|.||::|||..||.:..|
  Fly   113 LKLVYALASSMSDNYHNVKLCAYKQPG--NCTLRLIPEVQSIVQGSRDLDEIEYYWFEWRSRTGL 175

  Fly   184 WASLNFYTIVQSYQRAAKILEVP-VHKLWYR---YDSQEMLQQMEQAMTELRPAYQQLHAFVRQE 244
            .....|...:..|::.|::...| ....|:|   ...||.:..:::.|..|||.:.|.||.||..
  Fly   176 ATRSQFVDFMDLYKKTAQLNGYPRAEDYWFRSLELKGQETMNLLDRIMHGLRPLFLQFHAHVRGS 240

  Fly   245 LHKKYGSDVVNLNGPIPDHLFQQVLEQAWASGSILEDYYPRAQLPEFD--EYVSHL-------TA 300
            |.|.:|..:|..|.|.|.||.:..:..|:.  .:..::|.....||..  .....|       |.
  Fly   241 LRKMHGEHLVPRNRPYPQHLAEVFIGNAFR--RVEAEWYVDLPSPEIGLANITQELHRRGLSTTQ 303

  Fly   301 KTMVNESENFYTSLGFEPLSAEFHKNQLKEPNQDSPNDDC--RPSIFDLTPHVYLMYC---EKVS 360
            :...|.:| ::.:|||..|.........|..:.|  :|.|  :...:...|.....||   ::..
  Fly   304 RVFWNVAE-YFRALGFPQLENSLWTYAQKVSSDD--DDRCWHKAWRYYALPRTNFTYCPLNDEER 365

  Fly   361 FRKLMQYHSHMARVYYAQ--------QKSHLPSYYFKAYNLEFAVGEAVVLSASSPAHLTGRRLA 417
            |..:.:..|.:.  ||..        |:...|       |...|:|:...::||||..|  |:|.
  Fly   366 FFNMFEAQSDLQ--YYRAASIQPTLLQEEPFP-------NFSDAIGKCFSMAASSPRFL--RKLG 419

  Fly   418 -------KEVLSETALMSRLFRMAIHTILSIPLYYVHTKVMHDLLNDTVDMDTVNKHYWRLMEQH 475
                   ||:   .|.::||:...:..:..:|::||..:...::|...:..|. |:.||||.|.:
  Fly   420 MLRDNKWKEL---PARLNRLYIQGLRVVFLLPVFYVLDRYRVEVLAGHIKADD-NEAYWRLTELY 480

  Fly   476 AGIEAPSDRSEGAIDFPYKFYVNIDQSFQTQKFISEVLGYQFYREFC------KKSYNRGPLHNC 534
            .|..||:.|:....|.|.|..:.:|..: ...|:|.||.:|..:.||      :....|.||..|
  Fly   481 TGAAAPTKRTNEQFDVPAKLLMEVDDQY-ASNFLSIVLQFQLLKHFCTITGQFEMGNPRKPLDMC 544

  Fly   535 DFYGSLAVGNDLKAMMSLGSTKPWKQVVGKILPNNTGLSSLALLEYYQPVLDWLNKYNKDANSKI 599
            |......:|..||..|||||:..:::|: |:|.....:|...||.|:||:.|||...|::.|.::
  Fly   545 DLSDQRGIGEILKRAMSLGSSVHYREVL-KVLLGEPEISIDGLLTYFQPLQDWLQHQNQENNLEV 608

  Fly   600 GWT 602
            |||
  Fly   609 GWT 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance-4	NP_610442.2	M2_ACE	29..592	CDD:341055	158/613 (26%)
Ance-2	NP_788042.1	M2_ACE	26..601	CDD:341055	158/613 (26%)