Protein Alignment Ance-4 and acn-1

DIOPT Version :9

• Sequence 1: NP_610442.2
• Gene: Ance-4 / 35909
• FlyBaseID: FBgn0033366
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_001024453.1
• Gene: acn-1 / 180780
• WormBaseID: WBGene00000039
• Length: 906
• Species: Caenorhabditis elegans
• Alignment Length: 645
• Identity: 135/645 - (20%)
• Similarity: 263/645 - (40%)
• Gaps: 129/645 - (20%)

  Fly    20 ANIDLEAKTFVNQSSDRYYRFYNEIAAETYSANNE-EDFDALFSKLNNVKRIAEELVSISRQAAT 83
            |..:.||...:.:.:...:|::|:.:.....|.:| |:...:|.:            |.|.||..
 Worm   186 AGYEAEAIKVLREVALSGWRYFNDASPSLKLALDEAENVLTMFVR------------STSMQAKQ 238

  Fly    84 YDLDRIRSPQTKMALQELRTAGDLFVLGDDYFSSVQMNLAALQTLS-----TDKDIEPYLGGANM 143
            :|:..:...:....|..:...| :..|....|:......|||...|     .|||:.|
 Worm   239 FDMASVTDEKVMRQLGYVSFEG-MSALAPSRFADYSQAQAALNRDSKDSTICDKDVPP------- 295

  Fly   144 PNEDDSPLAYFP-DIQKIVQSSKDADELKYYWEAW-----RDK---NQL------WASLNFYTIV 193
                  |.|... |:..|.::.|||..|::.|.::     :.|   |.:      .|.||.:...
 Worm   296 ------PCALQKIDMDSIFRNEKDASRLQHLWVSYVTAIAKSKPSYNNIITISNEGAKLNGFANG 354

  Fly   194 QSYQRAAKILEVPVHKLWYRYDSQEMLQQMEQAMTELRPAYQQLHAFVRQELHKKYGSDV-VNLN 257
            .:..|:|..:...|||..:     ::.:|:::..:.::|.||.|||::|::|...|.:.| ::.:
 Worm   355 GAMWRSAFDMSSKVHKAEF-----DLNKQIDKIYSTIQPFYQLLHAYMRRQLAGIYSNPVGLSKD 414

  Fly   258 GPIPDHLFQQVLEQAWASGSILEDYY------------PRAQLPEFDEYVSHLTAKTMVNESENF 310
            ||||.|||..:....|::      :|            |.|.|..|:  ..:.|.|.|...:..:
 Worm   415 GPIPAHLFGSLDGGDWSA------HYEQTKPFEEESETPEAMLSAFN--TQNYTTKKMFVTAYRY 471

  Fly   311 YTSLGFEPLSAEF----------HKNQLKEP----NQDSPNDDCRPSIFDLTPHVYLMYCEKVSF 361
            :.|.||..|...:          .|:.:..|    :..:|||            ..:..|.::..
 Worm   472 FKSAGFPHLPKSYWTSSIFARVWSKDMICHPAAALDMRAPND------------FRVKACAQLGE 524

  Fly   362 RKLMQYHSHMARVYYAQQKSHLPSYYFKAYNLEF----------AVGEAVVLSASSPAHLTGRRL 416
            ....|.||.:.:.||        .|.:|..:|.|          |:..|....:::|.:|..::|
 Worm   525 PDFEQAHSLLVQTYY--------QYLYKDQSLLFREQASPVITDAIANAFAHLSTNPHYLYSQKL 581

  Fly   417 AKEV---LSETALMSRLFRMAIHTILSIPLYYVHTKVMHDLLNDTVDMDTVNKHYWRLMEQHAGI 478
            ....   :.::.::::|::.::.:...:|.........::|.:.||..:.:|..:|.:..::.|:
 Worm   582 VPSEHLDIKDSVIINKLYKESLESFTKLPFTIAADNWRYELFDGTVPKNKLNDRWWEIRNKYEGV 646

  Fly   479 EAPSDRSEGAIDFPYKFYVNIDQSFQTQKFISEVLGYQFYREFCKKS--YNRGPLHNCDFYGSLA 541
            .:|...:...:|......|:...|..|:..||.||.:|..:..|.:.  .:.|.:.:.|
 Worm   647 RSPQPYNTSNLDALIHNSVSQVHSPATRTLISYVLKFQILKALCPEGTILSEGCILSED------ 705

  Fly   542 VGNDLKAMMSLGSTKPWKQVVGKILPNNTGLSSLALLEYYQPVLDWLNKYNKDANSKIGW 601
            ....|:..|.|||:..|.:.: :::.....|.:..|||||:|:::||...|:.....:||
 Worm   706 TTEKLRETMKLGSSITWLKAL-EMISGKGELDAQPLLEYYEPLINWLRNTNEIDQVVVGW 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance-4	NP_610442.2	GluZincin	25..601	CDD:301352	132/638 (21%)
acn-1	NP_001024453.1	Peptidase_M2	175..764	CDD:279709	133/643 (21%)
		EB	<794..833	CDD:279949

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000442
OrthoInspector	1	1.000	-	-		otm14376
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10514
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010