Protein Alignment Ance-4 and LOC1279162

DIOPT Version :10

• Sequence 1: NP_610442.2
• Gene: Ance-4 / 35909
• FlyBaseID: FBgn0033366
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: XP_318842.5
• Gene: LOC1279162 / 1279162
• VectorBaseID: AGAMI1_008771
• Length: 621
• Species: Anopheles gambiae
• Alignment Length: 634
• Identity: 177/634 - (27%)
• Similarity: 298/634 - (47%)
• Gaps: 62/634 - (9%)

  Fly     3 LLLLLVLIAGI--GCATAAANIDLEAKTFVNQSSDRYYRFYNEIAAETYSANNEEDFDALFSKLN 65
            ::|...|:..:  |...:.::.:|||:.:|.|..:......|......::..::.:.|.|..|..
Mosquito     7 VILAFALVCCVLGGKLVSVSDDELEARRYVEQVDEEILSRRNVGTEAEWAYESDINEDNLMVKNE 71

  Fly    66 NVKRIAEELVSISRQAATYDLDRIRSPQTKMALQELRTAGDLFVLGDDYFSSVQMNLAALQTLST 130
            .....|..|..::.....|:.:.......|..:::|...| ..||.:|.|:.:   |.|:..:.
Mosquito    72 VAAANAVFLKEVANTLNKYEYESFSDEDLKRKIRKLTKLG-YSVLPEDTFAEM---LDAINRMQ- 131

  Fly   131 DKDIEPYLGGANMPNEDDS--PLAYFPDIQKIVQSSKDADELKYYWEAW--------RDKNQLWA 185
                |.|.........|:|  .||..|::.:|:.:|:|.:||||||:.|        ||..|.:.
Mosquito   132 ----ENYAKVKVCDYRDNSKCDLALEPELTEIMATSRDPEELKYYWQQWYDAAGAPTRDDFQKYV 192

  Fly   186 SLNFYTI-VQSYQRAAKILEVPVHKLWY-RYDSQEMLQQMEQAMTELRPAYQQLHAFVRQELHKK 248
            .||.... :.:|...|        :.|. .|:.....:|::..:.||||.|:|:||.||.:|.|.
Mosquito   193 DLNGVAARMNNYASGA--------EYWLSAYEDDTFEEQVDAVIEELRPLYEQIHANVRYQLRKY 249

  Fly   249 YGSDVVNLNGPIPDHLFQQVLEQAWASGSILEDYYPRAQLPEFDEYVSHLTAKTMVNESEN---- 309
            ||.:||:..||||.||...:..|.|.:.:.:...:|..||.:..|        .||.:..|
Mosquito   250 YGENVVSEKGPIPMHLLGNMWAQKWGNIADITSPFPDRQLLDVTE--------EMVRQGYNPIQM 306

  Fly   310 ------FYTSLGFEPLSAEFHKNQLKEPNQDSPNDDCRPSI--FDLTPHVYLMYCEKVSFRKLMQ 366
                  |:.|:....|.|.|.:..:.|...|..:..|..|.  |..|..|.:..|.:|:..:...
Mosquito   307 FEMGDKFFQSMNMTKLPATFWEKSILEKPDDGRDLVCHASAWEFSKTDDVRIKQCTRVTMEQFFT 371

  Fly   367 YHSHMARVYYAQQKSHLPSYYFKAYNLEF--AVGEAVVLSASSPAHLTGRRLAKE-VLSETALMS 428
            .|..:..|.|..|..||||.|....|..|  |||:.:.||.|:|.||....|.|: |..|.:.::
Mosquito   372 VHHELGHVQYFLQYQHLPSMYRDGANPGFHEAVGDVLSLSVSTPKHLEKIGLLKDYVEDEESKLN 436

  Fly   429 RLFRMAIHTILSIPLYYVHTKVMHDLLNDTVDMDTVNKHYWRLMEQHAGIEAPSDRSEGAIDFPY 493
            :.:..|::.::.:|..|...|....:....:..:..|..:|.:..:.:|:|.|..|||..:|.|.
Mosquito   437 QFYGSALNKLVFLPFAYTLDKYRWGIFRGDIKPEQYNCKFWEMRSKFSGVEPPVVRSESDLDAPA 501

  Fly   494 KFYVNIDQSFQTQKFISEVLGYQFYREFCKKS--YNRG----PLHNCDFYGSLAVGNDLKAMMSL 552
            |::|:.|..: .:.|:|.::.:||:|..|:|:  |.:|    .|:|||.|.|:.|||.:|||:.|
Mosquito   502 KYHVSADVEY-LRYFVSFIIQFQFHRAACEKAGEYVKGDPEKTLNNCDIYQSVEVGNAIKAMLEL 565

  Fly   553 GSTKPWKQVVGKILPNNTGLSSLALLEYYQPVLDWLNKYNKDANSKIGW 601
            ||:|||...: ::|.....:|:.||:||::|:.|||...|:...:.:||
Mosquito   566 GSSKPWPDAM-EVLTGERRMSADALIEYFRPLYDWLVIENERIGAHVGW 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance-4	NP_610442.2	M2_ACE	29..592	CDD:341055	168/595 (28%)
LOC1279162	XP_318842.5	None