Protein Alignment Ance-4 and Ace

DIOPT Version :9

• Sequence 1: NP_610442.2
• Gene: Ance-4 / 35909
• FlyBaseID: FBgn0033366
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_997507.1
• Gene: Ace / 11421
• MGIID: 87874
• Length: 1312
• Species: Mus musculus
• Alignment Length: 618
• Identity: 169/618 - (27%)
• Similarity: 284/618 - (45%)
• Gaps: 74/618 - (11%)

  Fly    22 IDLEAKTFVNQSSDRYYRFY--------NEIAAETYSANNEEDFDALFSKLNNVKRIAEELVSIS 78
            ||||..   ...:||:...|        ||.|...:..|.....:.....|.....::...:...
Mouse   645 IDLETD---EAKADRFVEEYDRTAQVLLNEYAEANWQYNTNITIEGSKILLEKSTEVSNHTLKYG 706

  Fly    79 RQAATYDLDRIRSPQTKMALQELRTAGDLFVLGDDYFSSVQMNLAALQTLSTDKDIEPYLGGANM 143
            .:|.|:|:...::...|..:::|:.. |..||...........|..::|..:..:| .|..|..|
Mouse   707 TRAKTFDVSNFQNSSIKRIIKKLQNL-DRAVLPPKELEEYNQILLDMETTYSLSNI-CYTNGTCM 769

  Fly   144 PNEDDSPLAYFPDIQKIVQSSKDADELKYYWEAWRDK----------------NQLWASLNFYTI 192
            |.|        ||:..::.:|:..:||.:.|::||||                |:: |.||.||.
Mouse   770 PLE--------PDLTNMMATSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKI-AKLNGYTD 825

  Fly   193 VQSYQRAAKILEVPVHKLWYRYDSQEMLQQMEQAMTELRPAYQQLHAFVRQELHKKYGSDVVNLN 257
            .....|:.             |:|..:.|.:|:...||:|.|..|||:||:.||:.|||:.:||:
Mouse   826 AGDSWRSL-------------YESDNLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLD 877

  Fly   258 GPIPDHLFQQVLEQAWASGSILEDYYPRAQLPEFDEYVSHL----TAKTMVNESENFYTSLGFEP 318
            ||||.||...:..|.|::...|...:|.|  |..|...:.:    |.:.:..|::||:||||..|
Mouse   878 GPIPAHLLGNMWAQTWSNIYDLVAPFPSA--PNIDATEAMIKQGWTPRRIFKEADNFFTSLGLLP 940

  Fly   319 LSAEF-HKNQLKEPNQDSPNDDCRPSIFDLTPHVY------LMYCEKVSFRKLMQYHSHMARVYY 376
            :..|| :|:.|::|. |.....|.||.:|.    |      :..|..|:...|:..|..|..:.|
Mouse   941 VPPEFWNKSMLEKPT-DGREVVCHPSAWDF----YNGKDFRIKQCTSVNMEDLVIAHHEMGHIQY 1000

  Fly   377 AQQKSHLPSYYFKAYNLEF--AVGEAVVLSASSPAHLTG-RRLAKEVLSETALMSRLFRMAIHTI 438
            ..|...||..:.:..|..|  |:|:.:.||.|:|.||.. ..|:.|.......::.|.:||:..|
Mouse  1001 FMQYKDLPVTFREGANPGFHEAIGDIMALSVSTPKHLYSLNLLSTEGSGYEYDINFLMKMALDKI 1065

  Fly   439 LSIPLYYVHTKVMHDLLNDTVDMDTVNKHYWRLMEQHAGIEAPSDRSEGAIDFPYKFYVNIDQSF 503
            ..||..|:..:....:.:.::..:..|:.:|.|..::.|:..|..||:|..|...||:|..:..:
Mouse  1066 AFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPY 1130

  Fly   504 QTQKFISEVLGYQFYREFCKKSYNRGPLHNCDFYGSLAVGNDLKAMMSLGSTKPWKQVVGKILPN 568
             .:.|:|.::.:||:...|:.:.:.||||.||.|.|...|..|...|.||.:|||.:.: |::..
Mouse  1131 -VRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAM-KLITG 1193

  Fly   569 NTGLSSLALLEYYQPVLDWLNKYNKDANSKIGW 601
            ...:|:.|::.|::|:.:||...|:.....:||
Mouse  1194 QPNMSASAMMNYFKPLTEWLVTENRRHGETLGW 1226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance-4	NP_610442.2	GluZincin	25..601	CDD:301352	164/613 (27%)
Ace	NP_997507.1	Peptidase M2 1	35..635
		Peptidase_M2	45..628	CDD:279709
		Peptidase M2 2	636..1237		169/618 (27%)
		Peptidase_M2	649..1226	CDD:279709	163/612 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3690
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000442
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10514
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910