DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8170 and TMPRSS13

DIOPT Version :9

Sequence 1:NP_610441.2 Gene:CG8170 / 35908 FlyBaseID:FBgn0033365 Length:855 Species:Drosophila melanogaster
Sequence 2:NP_001070731.1 Gene:TMPRSS13 / 84000 HGNCID:29808 Length:567 Species:Homo sapiens


Alignment Length:328 Identity:95/328 - (28%)
Similarity:150/328 - (45%) Gaps:69/328 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   552 TCDGLLRGCCHRTAKSAN---------LGSSDFVGNAVDLTDLPQKNYGPVNNEPS-CGISLAKQ 606
            ||..|.....|||.:.|:         |..:..:..::..::.|.:.|  ::.:.| ||:    :
Human   262 TCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLHRSECPSQRY--ISLQCSHCGL----R 320

  Fly   607 TAQRRIVGGDDAGFGSFPWQAYIRIGSSR-CGGSLISRRHVVTAGHC--VAR----------ATP 658
            ....|||||..|....:|||..:..|::. |||:||..:.|:||.||  |.|          |..
Human   321 AMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGT 385

  Fly   659 RQVH-----VTLGDYVINSAVEPLPAYTFGVRRIDVHPYFKFTPQADRFDISVLTLERTVHFMPH 718
            ..:|     .::.:.:|||                     .:|.:.|.:||:::.|.:.:....|
Human   386 SNLHQLPEAASIAEIIINS---------------------NYTDEEDDYDIALMRLSKPLTLSAH 429

  Fly   719 IAPICLPEKNEDF-LGKFGWAAGWGALNPGSRLRPKTLQAVDVPVIENRICERWHRQNGINVVIY 782
            |.|.|||...:.| |.:..|..|:|............|:.|.|.:|:.:.|.        :.::|
Human   430 IHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCN--------DYLVY 486

  Fly   783 Q-----EMLCAGYRNGGKDSCQGDSGGPLMHDKNGRWYLIGVVSAGYSCASRGQPGIYHSVSKTV 842
            .     .|:|||...||:|||||||||||:.::|.||||.||.|.|..|..|.:||:|..|::.:
Human   487 DSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVL 551

  Fly   843 DWV 845
            .|:
Human   552 PWI 554

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8170NP_610441.2 Tryp_SPc 611..845 CDD:214473 81/257 (32%)
Tryp_SPc 612..846 CDD:238113 81/258 (31%)
TMPRSS13NP_001070731.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..115
13 X 5 AA repeats of A-S-P-A-[GLQR] 9..93
4 X 5 AA repeats of T-P-P-G-R 14..68
DUF3682 16..>87 CDD:289231
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 131..157
SRCR_2 231..320 CDD:292133 13/63 (21%)
Tryp_SPc 325..554 CDD:214473 81/257 (32%)
Tryp_SPc 326..557 CDD:238113 81/258 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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