Protein Alignment CG8170 and PRSS22

DIOPT Version :10

• Sequence 1: NP_610441.2
• Gene: CG8170 / 35908
• FlyBaseID: FBgn0033365
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 93/261 - (35%)
• Similarity: 141/261 - (54%)
• Gaps: 18/261 - (6%)

  Fly   597 PSCGISLAKQTAQRRIVGGDDAGFGSFPWQAYI-RIGSSRCGGSLISRRHVVTAGHCVA--RATP 658
            |:||    |.....|:|||:|:....:||...| :.|:..|.|||::.|.|:||.||..  ...|
Human   147 PACG----KPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKP 207

  Fly   659 RQVHVTLGDYVINSAVEPLP---AYTFGVRRIDVHPYFKFTPQADRFDISVLTLERTVHFMPHIA 720
            ....|.||.:.:.:     |   :...||..::.||.:.:...|.. ||:::.|||::.|...:.
Human   208 YLFSVLLGAWQLGN-----PGSRSQKVGVAWVEPHPVYSWKEGACA-DIALVRLERSIQFSERVL 266

  Fly   721 PICLPEKNEDF-LGKFGWAAGWGALNPGSRL-RPKTLQAVDVPVIENRICERWHRQNGINVVIYQ 783
            |||||:.:... .....|.:|||::..|..| .|:|||.:.||:|::.:|...:.:......|.:
Human   267 PICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITE 331

  Fly   784 EMLCAGYRNGGKDSCQGDSGGPLMHDKNGRWYLIGVVSAGYSCASRGQPGIYHSVSKTVDWVSYV 848
            :||||||..|.:|:|.||||||||...:|.|.|.|::|.|..||.|.:||:|.|:|....||..:
Human   332 DMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKI 396

  Fly   849 V 849
            |
Human   397 V 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8170	NP_610441.2	Tryp_SPc	612..846	CDD:238113	86/241 (36%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	87/243 (36%)