Protein Alignment CG8170 and Hgfac

DIOPT Version :10

• Sequence 1: NP_610441.2
• Gene: CG8170 / 35908
• FlyBaseID: FBgn0033365
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_445772.1
• Gene: Hgfac / 58947
• RGDID: 70909
• Length: 653
• Species: Rattus norvegicus
• Alignment Length: 636
• Identity: 158/636 - (24%)
• Similarity: 219/636 - (34%)
• Gaps: 199/636 - (31%)

  Fly   384 RPQRGFYFGDTEFRTGPPAP---VRQFGP-----QKNFQEYV-----GPSEYQGTRKSRYYPYKS 435
            :||.|      ...|.||.|   ..:..|     ..||...:     |.:|.:|.:..||. ..|
  Rat    31 QPQAG------RNHTEPPGPNVTATRMTPMIPATSGNFSTSIGSDPEGEAETEGPQSERYL-LSS 88

  Fly   436 SRSP---RVV--------FP-----------------------TNDNV-----------GTTGPS 455
            |.||   :|:        ||                       |..|.           .|....
  Rat    89 SSSPLGGQVLTESGQPCRFPFRYGGRMLHSCSSEGSAYRKWCATTHNYDRDRAWGYCAEATLPVE 153

  Fly   456 GPA----GSSGPSGNGVYFSDN-----------IAFRDQNFGINELAAVQDVRNDY-SLQD-LDS 503
            |||    .:|||..||...|..           :||..::.|..:  ...:.|.:| .:.| ...
  Rat   154 GPAVLDPCASGPCLNGGTCSSTQDHVSYHCACPLAFTGKDCGTEK--CFDETRYEYFEVGDHWAR 216

  Fly   504 ASEATSSPQSASTFKEKVDITTDTECQH----RGGTCEFFLG----------------------- 541
            .||......|....:.:.:.|..|.|..    .||||...:|
  Rat   217 VSEGHVEQCSCIEGQARCEDTHHTACLSSPCLNGGTCHLIVGTGTSICACPLGYAGRFCNIVPTE 281

  Fly   542 -CWLSG-----GLIQGTCDGLL---------------------------------------RGCC 561
             |:|..     |:...:..||.                                       |..|
  Rat   282 RCFLGNGTEYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDKDERPWC 346

  Fly   562 HRTAKSA------NLGSSDFVGNAVD-----LTDLPQKNYGPVNNEPSCGISLAKQTAQR-RIVG 614
            :....||      .|.:.:.:.....     |..||:..   ....|:||....|:|..| ||:|
  Rat   347 YVVKDSALSWEYCRLAACESLARVHSRIPEVLATLPEST---STARPTCGKRHKKRTFLRPRIIG 408

  Fly   615 GDDAGFGSFPWQAYIRIGSSRCGGSLISRRHVVTAGHCVARATPR-QVHVTLGDYVINS------ 672
            |..:..||.||.|.|.||:..|.|||:....||:|.||.:.:.|| .:.|.||.:..|.
  Rat   409 GSSSLPGSHPWLAAIYIGNGFCAGSLVHTCWVVSAAHCFSSSPPRDSITVVLGQHFFNRTTDVTQ 473

  Fly   673 --AVEPLPAYTFGVRRIDVHPYFKFTPQADRFDISVLTL----ERTVHFMPHIAPICLPEKNEDF 731
              |:|....||.         |..|.|  :..|:.::.|    ||.......:.||||||....|
  Rat   474 TFAIEKYVPYTL---------YSVFNP--NDHDLVLIRLKKKGERCAVRSQFVQPICLPEAGSSF 527

  Fly   732 -LGKFGWAAGWGALNPGSRLRPKTLQAVDVPVIENRICERWHRQNGINVVIYQEMLCAGYRNGGK 795
             .|.....||||.::........:|....||::.:..|.   ........|...||||||.:...
  Rat   528 PTGHKCQIAGWGHMDENVSGYSNSLLEALVPLVADHKCS---SPEVYGADISPNMLCAGYFDCKS 589

  Fly   796 DSCQGDSGGPLMHDKNGRWYLIGVVSAGYSCASRGQPGIYHSVSKTVDWVS 846
            |:|||||||||:.:|||..||.|::|.|..|....:||:|..||..|||::
  Rat   590 DACQGDSGGPLVCEKNGVAYLYGIISWGDGCGRLNKPGVYTRVSNYVDWIN 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8170	NP_610441.2	Tryp_SPc	612..846	CDD:238113	87/247 (35%)
Hgfac	NP_445772.1	FN2	99..145	CDD:128373	4/45 (9%)
		EGF_CA	159..194	CDD:238011	8/34 (24%)
		FN1	197..237	CDD:238018	6/41 (15%)
		EGF	242..274	CDD:394967	6/31 (19%)
		Kringle	283..364	CDD:395005	10/80 (13%)
		Tryp_SPc	406..641	CDD:238113	87/249 (35%)