Protein Alignment CG8170 and PRSS8

DIOPT Version :10

• Sequence 1: NP_610441.2
• Gene: CG8170 / 35908
• FlyBaseID: FBgn0033365
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_002764.1
• Gene: PRSS8 / 5652
• HGNCID: 9491
• Length: 343
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 100/273 - (36%)
• Similarity: 135/273 - (49%)
• Gaps: 38/273 - (13%)

  Fly   591 GPVNNEPSCGISLAKQTAQRRIVGGDDAGFGSFPWQAYIRI-GSSRCGGSLISRRHVVTAGHCVA 654
            |....|..||::     .|.||.||..|..|.:|||..|.. |...|||||:|.:.|::|.||.
Human    29 GAEGAEAPCGVA-----PQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCF- 87

  Fly   655 RATPRQVH-----VTLGDYVINSAVEPLPAYTFGVRRIDVHPYFKFTPQADRFDISVLTLERTVH 714
               |.:.|     |.||.:.::|..|.....|..    |:.|:..:..:..:.||::|.|.|.:.
Human    88 ---PSEHHKEAYEVKLGAHQLDSYSEDAKVSTLK----DIIPHPSYLQEGSQGDIALLQLSRPIT 145

  Fly   715 FMPHIAPICLPEKNEDF-LGKFGWAAGWGALNPG-SRLRPKTLQAVDVPVIENRIC--------- 768
            |..:|.|||||..|..| .|......|||.:.|. |.|.||.||.::||:|....|
Human   146 FSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAK 210

  Fly   769 -ERWHRQNGINVVIYQEMLCAGYRNGGKDSCQGDSGGPLMHDKNGRWYLIGVVSAGYSCASRGQP 832
             |..|       .:.::|:||||..||||:|||||||||.....|.|||.|:||.|.:|.:|.:|
Human   211 PEEPH-------FVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRP 268

  Fly   833 GIYHSVSKTVDWV 845
            |:|...|....|:
Human   269 GVYTLASSYASWI 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8170	NP_610441.2	Tryp_SPc	612..846	CDD:238113	94/252 (37%)
PRSS8	NP_002764.1	Tryp_SPc	45..284	CDD:238113	94/252 (37%)