Protein Alignment CG8170 and KLK7

DIOPT Version :10

• Sequence 1: NP_610441.2
• Gene: CG8170 / 35908
• FlyBaseID: FBgn0033365
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 76/259 - (29%)
• Similarity: 114/259 - (44%)
• Gaps: 39/259 - (15%)

  Fly   601 ISLAKQTAQR-----RIVGGDDAGFGSFPWQAYIRIGSS-RCGGSLISRRHVVTAGHCVARATPR 659
            :|||.:||..     :|:.|.....||.|||..:..|:. .|||.|::.|.|:||.||  :....
Human    14 LSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC--KMNEY 76

  Fly   660 QVHV---TLGDYVINSAVEPLPAYTFGVRRIDVHPYFK---FTPQADRFDISVLTLERTVHFMPH 718
            .||:   ||||.              ..:||.....|:   ::.|....|:.::.|.........
Human    77 TVHLGSDTLGDR--------------RAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSM 127

  Fly   719 IAPICLPEKNEDFLGKFGWAAGWGALNPGSRLRPKTLQAVDVPVIENRICERWHRQNGINVVIYQ 783
            :..:.||.:.|. .|.....:|||.........|..|..|||.:|..:.|.:.::.     ::..
Human   128 VKKVRLPSRCEP-PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD-----LLEN 186

  Fly   784 EMLCAGYRNGGKDSCQGDSGGPLMHDKNGRWYLIGVVSAG-YSCASRGQPGIYHSVSKTVDWVS 846
            .|||||..:..|::|.|||||||:    .|..|.|:||.| :.|.....||:|..|.|...|::
Human   187 SMLCAGIPDSKKNACNGDSGGPLV----CRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8170	NP_610441.2	Tryp_SPc	612..846	CDD:238113	71/241 (29%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	70/241 (29%)